trans-2,2-dimethyl-3-(p-tolylsulfonyl)cyclopropyl phenyl sulfide

Base Information

• Chemical Name: trans-2,2-dimethyl-3-(p-tolylsulfonyl)cyclopropyl phenyl sulfide
• CAS No.: 107697-02-9
• Molecular Formula: C₁₈H₂₀O₂S₂
• Molecular Weight: 332.488
• Mol file: 107697-02-9.mol

Synonyms:trans-2,2-dimethyl-3-(p-tolylsulfonyl)cyclopropyl phenyl sulfide

Chemical Property of trans-2,2-dimethyl-3-(p-tolylsulfonyl)cyclopropyl phenyl sulfide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of trans-2,2-dimethyl-3-(p-tolylsulfonyl)cyclopropyl phenyl sulfide

There total 7 articles about trans-2,2-dimethyl-3-(p-tolylsulfonyl)cyclopropyl phenyl sulfide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

3,3-dimethyl-1-(p-tolylsulfonyl)-2-(trimethylsilyl)-cyclopropene (107696-98-0) + thiophenol (108-98-5) → trans-2,2-dimethyl-3-(p-tolylsulfonyl)cyclopropyl phenyl sulfide (107697-02-9)

Guidance literature:

With sodium hydroxide; In methanol;

DOI:10.1016/S0040-4039(00)84583-9

Reference yield:

3,3-dimethyl-4-(p-tolylsulfonyl)-5-(trimethylsilyl)-3H-pyrazole (110355-39-0) → trans-2,2-dimethyl-3-(p-tolylsulfonyl)cyclopropyl phenyl sulfide (107697-02-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 99 percent / benzene / 2 h / Irradiation

2: 1.) KOH / 1.) aq. EtOH, 25 deg C, 10 min, 2.) aq. EtOH, reflux, 3 h

With potassium hydroxide; In benzene;

DOI:10.1021/jo00230a020

Reference yield:

[1-Diazo-3-methyl-2-(toluene-4-sulfonyl)-but-2-enyl]-trimethyl-silane (110355-40-3) → trans-2,2-dimethyl-3-(p-tolylsulfonyl)cyclopropyl phenyl sulfide (107697-02-9)

Guidance literature:

Multi-step reaction with 2 steps

1: benzene / Irradiation

2: 1.) KOH / 1.) aq. EtOH, 25 deg C, 10 min, 2.) aq. EtOH, reflux, 3 h

With potassium hydroxide; In benzene;

DOI:10.1021/jo00230a020

upstream raw materials:

trans-<2,2-dimethyl-1-(phenylthio)-3-(p-tolylsulfonyl)cyclopropyl>trimethylsilane

cis-<2,2-dimethyl-1-(phenylthio)-3-(p-tolylsulfonyl)cyclopropyl>trimethylsilane

3,3-dimethyl-1-(p-tolylsulfonyl)-2-(trimethylsilyl)-cyclopropene

thiophenol

Downstream raw materials:

C₁₈H₁₉⁽²⁾HO₂S₂

methyl trans-2,2-dimethyl-1-(p-tolylsulfonyl)-3-(phenylthio)cyclopropanecarboxylate

methyl cis-2,2-dimethyl-1-(p-tolylsulfonyl)-3-(phenylthio)cyclopropanecarboxylate

methyl trans-2,2-dimethyl-3-(phenylsulfonyl)-1-(p-tolylsulfonyl)cyclopropanecarboxylate