methyl 2-{[4-(chlorosulfonyl)-2,3-dimethylphenyl]oxy}propanoate

Base Information

• Chemical Name: methyl 2-{[4-(chlorosulfonyl)-2,3-dimethylphenyl]oxy}propanoate
• CAS No.: 1304581-32-5
• Molecular Formula: C₁₂H₁₅ClO₅S
• Molecular Weight: 306.767
• Mol file: 1304581-32-5.mol

Synonyms:methyl 2-{[4-(chlorosulfonyl)-2,3-dimethylphenyl]oxy}propanoate

Chemical Property of methyl 2-{[4-(chlorosulfonyl)-2,3-dimethylphenyl]oxy}propanoate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of methyl 2-{[4-(chlorosulfonyl)-2,3-dimethylphenyl]oxy}propanoate

There total 2 articles about methyl 2-{[4-(chlorosulfonyl)-2,3-dimethylphenyl]oxy}propanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

methyl 2-[(2,3-dimethylphenyl)oxy]propanoate (153472-74-3) → methyl 2-{[4-(chlorosulfonyl)-2,3-dimethylphenyl]oxy}propanoate (1304581-32-5)

Guidance literature:

With chlorosulfonic acid; at 0 - 20 ℃; Inert atmosphere;

DOI:10.1016/j.bmcl.2011.02.077

Reference yield:

2,3-Dimethylphenol (526-75-0) → methyl 2-{[4-(chlorosulfonyl)-2,3-dimethylphenyl]oxy}propanoate (1304581-32-5)

Guidance literature:

Multi-step reaction with 2 steps

1: potassium carbonate / N,N-dimethyl-formamide / 0.17 h / 170 °C / Microwave irradiation

2: chlorosulfonic acid / 0 - 20 °C / Inert atmosphere

With chlorosulfonic acid; potassium carbonate; In N,N-dimethyl-formamide;

DOI:10.1016/j.bmcl.2011.02.077

Reference yield:

methyl 2-{[4-(chlorosulfonyl)-2,3-dimethylphenyl]oxy}propanoate (1304581-32-5) + 3-bromo-2-methoxyphenylamine (116557-46-1) → C19H22BrNO6S

Guidance literature:

With pyridine; for 16h;

DOI:10.1016/j.bmcl.2011.02.077

upstream raw materials:

2,3-Dimethylphenol

methyl 2-[(2,3-dimethylphenyl)oxy]propanoate

Downstream raw materials:

C₂₇H₃₀ClNO₅S