116557-46-1

Basic information

• Product Name: 2-amino-6-bromoanisole
• Synonyms: 2-Amino-6-bromoanisole, 3-Bromo-o-anisidine;2-amino-6-bromoanisole;BenzenaMine, 3-broMo-2-Methoxy-;3-Bromo-o-anisidine
• CAS NO: 116557-46-1
• Molecular Formula: C₇H₈BrNO
• Molecular Weight: 202
• Mol File: 116557-46-1.mol
• Article Data: 12

Chemical Properties

• Melting Point: 65℃
• Boiling Point: 268℃
• Flash Point: 116℃
• Appearance: /
• Density: 1.531
• Refractive Index: 1.5430 to 1.5470
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• PKA: 3.46±0.10(Predicted)
• CAS DataBase Reference: 2-amino-6-bromoanisole(CAS DataBase Reference)
• NIST Chemistry Reference: 2-amino-6-bromoanisole(116557-46-1)
• EPA Substance Registry System: 2-amino-6-bromoanisole(116557-46-1)

Safety Data

• RIDADR: UN 2810 6.1/PG III
• HazardClass: 6.1
• PackingGroup: III
• Hazardous Substances Data: 116557-46-1(Hazardous Substances Data)

Usage

General Description

2-amino-6-bromoanisole, also known as 6-Bromo-2-aminophenol, is a chemical compound that consists of a bromine atom, an amino group, and a methoxy group attached to a benzene ring. It is a pale yellow to brown crystalline solid with a strong odor. 2-amino-6-bromoanisole is used in the synthesis of pharmaceuticals, dyes, and other organic compounds. It is also utilized as an intermediate for the production of various chemicals and can be used as a building block for the synthesis of new materials. Additionally, 2-amino-6-bromoanisole has been studied for its potential applications in medicinal chemistry, particularly in the development of new drugs.

Upstream product

• 67-56-1 methanol 
• 28165-50-6 2-amino-6-bromophenol 
• 13073-25-1 2-bromo-6-nitro-phenol 
• 74-88-4 methyl iodide 
• 578-57-4 2-bromoanisole 
• 98775-19-0 2-bromo-6-nitrophenyl methyl ether 

Downstream Products

• 860584-68-5 2-bromo-6-iodoanisole 
• 1449428-28-7 3-bromo-2-methoxy-N,N-bis(2-methoxyphenyl)-aniline 
• 1555699-65-4 2-(6-bromo-3,3-diethyl-7-methoxyindolin-1-yl)aniline 
• 1388032-47-0 (3-bromo-2-methoxyphenyl)hydrazine 
• 1609531-35-2 2-methoxy-3-(1-methyl-1H-pyrazol-4-yl) aniline 

Relevant articles and documents

AMIDE-SUBSTITUTED HETEROCYCLIC COMPOUNDS FOR THE TREATMENT OF CONDITIONS RELATED TO THE MODULATION OF IL-12, IL-23 AND/OR IFN-ALPHA

Compounds having the following formula I: or a stereoisomer or pharmaceutically-acceptable salt thereof, where R1, R2, R3, R4, and R5 are as defined herein, are useful in the modulation of IL-12, IL-2

ALKYL-AMIDE-SUBSTITUTED PYRIDYL COMPOUNDS USEFUL AS MODULATORS OF IL-12, IL-23 AND/OR IFNα RESPONSES

Compounds having the following formula I: or a stereoisomer or a pharmaceutically-acceptable salt thereof, wherein R1, R2, R3, R4, and R5 are as defined herein, are useful in the modulation of IL-12, IL-23 and/or IFNα by acting on Tyk-2 to cause signal transduction inhibition.

ALKYL-AMIDE-SUBSTITUTED PYRIDYL COMPOUNDS USEFUL AS MODULATORS OF IL-12, IL-23 AND/OR IFNALPHA RESPONSES

Compounds having the following formula (I): or a stereoisomer or a pharmaceutically-acceptable salt thereof, wherein R1, R2, R3, R4, and R5 are as defined herein, are useful in the modulation of IL-12, IL-23 and/or IFNα by acting on Tyk-2 to cause signal transduction inhibition.