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2-amino-6-bromoanisole, also known as 6-Bromo-2-aminophenol, is a chemical compound characterized by the presence of a bromine atom, an amino group, and a methoxy group attached to a benzene ring. It is a pale yellow to brown crystalline solid with a strong odor, and is recognized for its role in the synthesis of various organic compounds and its potential in medicinal chemistry.

116557-46-1

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116557-46-1 Usage

Uses

Used in Pharmaceutical Synthesis:
2-amino-6-bromoanisole is used as a key intermediate in the synthesis of pharmaceuticals for its ability to contribute to the development of new drugs, enhancing the range of therapeutic options available.
Used in Dye Production:
In the dye industry, 2-amino-6-bromoanisole is utilized as a building block for the production of dyes, leveraging its chemical structure to create a variety of colorants for different applications.
Used in Organic Compound Synthesis:
2-amino-6-bromoanisole serves as a versatile intermediate in the synthesis of other organic compounds, contributing to the creation of a diverse array of chemical products.
Used in Medicinal Chemistry Research:
2-amino-6-bromoanisole is employed in medicinal chemistry research as a potential component in the development of innovative drugs, exploring its properties to advance pharmaceutical formulations.

Check Digit Verification of cas no

The CAS Registry Mumber 116557-46-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,6,5,5 and 7 respectively; the second part has 2 digits, 4 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 116557-46:
(8*1)+(7*1)+(6*6)+(5*5)+(4*5)+(3*7)+(2*4)+(1*6)=131
131 % 10 = 1
So 116557-46-1 is a valid CAS Registry Number.

116557-46-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 10, 2017

Revision Date: Aug 10, 2017

1.Identification

1.1 GHS Product identifier

Product name 3-Bromo-2-methoxyaniline

1.2 Other means of identification

Product number -
Other names 3-bromo-2-methoxyaniline

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:116557-46-1 SDS

116557-46-1Relevant academic research and scientific papers

AMIDE-SUBSTITUTED HETEROCYCLIC COMPOUNDS FOR THE TREATMENT OF CONDITIONS RELATED TO THE MODULATION OF IL-12, IL-23 AND/OR IFN-ALPHA

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Page/Page column 192-193, (2020/05/29)

Compounds having the following formula I: or a stereoisomer or pharmaceutically-acceptable salt thereof, where R1, R2, R3, R4, and R5 are as defined herein, are useful in the modulation of IL-12, IL-2

TYK2 INHIBITORS AND USES THEREOF

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Paragraph 00487; 00495; 00496, (2018/05/15)

The present invention provides compounds, compositions thereof, and methods of using the same for the inhibition of TYK2, and the treatment of TYK2-mediated disorders.

ALKYL-AMIDE-SUBSTITUTED PYRIDYL COMPOUNDS USEFUL AS MODULATORS OF IL-12, IL-23 AND/OR IFNα RESPONSES

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Page/Page column 87, (2017/09/02)

Compounds having the following formula I: or a stereoisomer or a pharmaceutically-acceptable salt thereof, wherein R1, R2, R3, R4, and R5 are as defined herein, are useful in the modulation of IL-12, IL-23 and/or IFNα by acting on Tyk-2 to cause signal transduction inhibition.

NOVEL COMPOUND WITH ANTIBACTERIAL ACTIVITY

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Paragraph 0131, (2016/04/26)

A compound represented by the general formula (I) or a salt thereof having a potent antibacterial activity against bacteria that have acquired resistance to quinolones, and a medicament for prophylactic and/or therapeutic treatment of an infectious disease containing the compound or a salt thereof as an active ingredient, as well as a medicament for prophylactic and/or therapeutic treatment of an infectious disease containing a combination of the compound or a salt thereof, and a quinolone.

ALKYL-AMIDE-SUBSTITUTED PYRIDYL COMPOUNDS USEFUL AS MODULATORS OF IL-12, IL-23 AND/OR IFNALPHA RESPONSES

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Paragraph 00185, (2015/05/26)

Compounds having the following formula (I): or a stereoisomer or a pharmaceutically-acceptable salt thereof, wherein R1, R2, R3, R4, and R5 are as defined herein, are useful in the modulation of IL-12, IL-23 and/or IFNα by acting on Tyk-2 to cause signal transduction inhibition.

7-HYDROXY-INDOLINYL ANTAGONISTS OF P2Y1 RECEPTOR

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Paragraph 00162, (2014/02/16)

The present invention provides compounds of Formula (I): Formula (I) as defined in the specification and compositions comprising any of such novel compounds. These compounds are antagonists of P2Y1 receptor which may be used medicaments.

AMIDE-SUBSTITUTED HETEROCYCLIC COMPOUNDS USEFUL AS MODULATORS OF IL-12, IL-23 AND/OR IFN ALPHα RESPONSES

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Paragraph 00173, (2014/05/24)

Compounds having the following formula I: or a stereoisomer or pharmaceutically-acceptable salt thereof, where R1, R2, R3, R4, and R5 are as defined herein, are useful in the modulation of IL-12, IL-23 and/or IFNa, by acting on Tyk-2 to cause signal transduction inhibition.

INDOLINONE ANALOGUES

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Paragraph 0258; 0259, (2014/10/16)

The present invention encompasses compounds of general formula (I) wherein the groups R1 to R4, A1 and A2 have the meanings given in the claims and in the specification. The compounds of the invention are suitable for the treatment of diseases characterized by excessive or abnormal cell proliferation pharmaceutical preparations containing such compounds and their uses as a medicament.

INDOLINONE ANALOGUES AS BRD4 INHIBITORS

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Page/Page column 55-56, (2014/10/15)

The present invention encompasses compounds of general formula (I) wherein the groups R1 to R4, A1 and A2 have the meanings given in the claims and in the specification. The compounds of the invention are suitable for the treatment of diseases characterized by excessive or abnormal cell proliferation pharmaceutical preparations containing such compounds and their uses as a medicament.

ALKYL-AMIDE-SUBSTITUTED PYRIDYL COMPOUNDS USEFUL AS MODULATORS OF IL-12, IL-23 AND/OR IFNα RESPONSES

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Paragraph 00236, (2014/05/24)

Compounds having the following formula (I): or a stereoisomer or pharmaceutically-acceptable salt thereof, where R1, R2, R3, R4, and R5 are as defined herein, are useful in the modulation of IL-12, IL-23 and/or IFNα, by acting on Tyk-2 to cause signal transduction inhibition.

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