6-hydroxymethyl veratraldehyde dimethyl acetal

Base Information

• Chemical Name: 6-hydroxymethyl veratraldehyde dimethyl acetal
• CAS No.: 76885-47-7
• Molecular Formula: C₁₂H₁₈O₅
• Molecular Weight: 242.272
• Mol file: 76885-47-7.mol

Synonyms:6-hydroxymethyl veratraldehyde dimethyl acetal

Chemical Property of 6-hydroxymethyl veratraldehyde dimethyl acetal

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

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Technology Process of 6-hydroxymethyl veratraldehyde dimethyl acetal

There total 2 articles about 6-hydroxymethyl veratraldehyde dimethyl acetal which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

formaldehyd (50-00-0,30525-89-4,61233-19-0) + 2-bromo-4,5-dimethoxybenzaldehyde dimethyl acetal (70461-33-5) → 6-hydroxymethyl veratraldehyde dimethyl acetal (76885-47-7)

Guidance literature:

With n-butyllithium; In diethyl ether; for 1h; Ambient temperature;

Reference yield:

2-bromo-4,5-dimethoxybenzaldehyde (5392-10-9) → 6-hydroxymethyl veratraldehyde dimethyl acetal (76885-47-7)

Guidance literature:

Multi-step reaction with 2 steps

1: Dowex 50W-X₈ acid exchange resin / methanol / 20 h / Heating

2: 95 percent / 1.) n-BuLi / diethyl ether / 1 h / Ambient temperature

With n-butyllithium; Dowex 50W-X₈ acid exchange resin; In methanol; diethyl ether;

upstream raw materials:

formaldehyd

2-bromo-4,5-dimethoxybenzaldehyde dimethyl acetal

2-bromo-4,5-dimethoxybenzaldehyde