2,2,4,4-Tetramethyl-oxazolidine-3-carboxylic acid (S)-2-dibenzylamino-propyl ester

Base Information

Chemical Name:2,2,4,4-Tetramethyl-oxazolidine-3-carboxylic acid (S)-2-dibenzylamino-propyl ester
CAS No.:247576-10-9
Molecular Formula:C₂₅H₃₄N₂O₃
Molecular Weight:410.557
Hs Code.:

Synonyms:2,2,4,4-Tetramethyl-oxazolidine-3-carboxylic acid (S)-2-dibenzylamino-propyl ester

Suppliers and Price of 2,2,4,4-Tetramethyl-oxazolidine-3-carboxylic acid (S)-2-dibenzylamino-propyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 2,2,4,4-Tetramethyl-oxazolidine-3-carboxylic acid (S)-2-dibenzylamino-propyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2,2,4,4-Tetramethyl-oxazolidine-3-carboxylic acid (S)-2-dibenzylamino-propyl ester

There total 2 articles about 2,2,4,4-Tetramethyl-oxazolidine-3-carboxylic acid (S)-2-dibenzylamino-propyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

: 146176-60-5
2,2,4,4-tetramethyl-1,3-oxazolidine-3-carbonyl chloride

: 60479-65-4
(S)-2-(N,N-dibenzylamino)-1-propanol

: 247576-10-9
2,2,4,4-Tetramethyl-oxazolidine-3-carboxylic acid (S)-2-dibenzylamino-propyl ester

Guidance literature:: (S)-2-(N,N-dibenzylamino)-1-propanol; With sodium hydride; In tetrahydrofuran; for 1h; Heating;

2,2,4,4-tetramethyl-1,3-oxazolidine-3-carbonyl chloride; In tetrahydrofuran; for 6h; Heating;
DOI:10.1055/s-1999-3575

Reference yield:

: 111060-49-2
N,N-dibenzyl-L-alanine benzyl ester

: 247576-10-9
2,2,4,4-Tetramethyl-oxazolidine-3-carboxylic acid (S)-2-dibenzylamino-propyl ester

Guidance literature:: Multi-step reaction with 2 steps

1.1: LiAlH₄ / tetrahydrofuran / Heating

2.1: NaH / tetrahydrofuran / 1 h / Heating

2.2: 83 percent / tetrahydrofuran / 6 h / Heating

With lithium aluminium tetrahydride; sodium hydride; In tetrahydrofuran; 1.1: Reduction / 2.1: Metallation / 2.2: Acylation;
DOI:10.1055/s-1999-3575

Reference yield: 64.0%

: 79-22-1
methyl chloroformate

: 247576-10-9
2,2,4,4-Tetramethyl-oxazolidine-3-carboxylic acid (S)-2-dibenzylamino-propyl ester

: 2,2,4,4-Tetramethyl-oxazolidine-3-carboxylic acid (1R,2S)-2-dibenzylamino-1-methoxycarbonyl-propyl ester

Guidance literature:: 2,2,4,4-Tetramethyl-oxazolidine-3-carboxylic acid (S)-2-dibenzylamino-propyl ester; With sec.-butyllithium; (-)-sparteine; In diethyl ether; hexane; cyclohexane; at -78 ℃;

methyl chloroformate; In diethyl ether; hexane; cyclohexane; at -78 - 20 ℃; for 12h;
DOI:10.1055/s-1999-3575