6-chloro-3-cyclohexylmethyl-1,1-dioxo-1,2(4)-dihydro-1λ⁶-benzo[1,2,4]thiadiazine-7-sulfonic acid amide

Base Information

• Chemical Name: 6-chloro-3-cyclohexylmethyl-1,1-dioxo-1,2(4)-dihydro-1λ⁶-benzo[1,2,4]thiadiazine-7-sulfonic acid amide
• CAS No.: 106321-01-1
• Molecular Formula: C₁₄H₁₈ClN₃O₄S₂
• Molecular Weight: 391.9
• Mol file: 106321-01-1.mol

Synonyms:6-chloro-3-cyclohexylmethyl-1,1-dioxo-1,2(4)-dihydro-1λ⁶-benzo[1,2,4]thiadiazine-7-sulfonic acid amide

Chemical Property of 6-chloro-3-cyclohexylmethyl-1,1-dioxo-1,2(4)-dihydro-1λ⁶-benzo[1,2,4]thiadiazine-7-sulfonic acid amide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 6-chloro-3-cyclohexylmethyl-1,1-dioxo-1,2(4)-dihydro-1λ⁶-benzo[1,2,4]thiadiazine-7-sulfonic acid amide

There total 2 articles about 6-chloro-3-cyclohexylmethyl-1,1-dioxo-1,2(4)-dihydro-1λ⁶-benzo[1,2,4]thiadiazine-7-sulfonic acid amide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-benzyl-6-chloro-1,1-dioxo-1,2(4)-dihydro-1λ6-benzo[1,2,4]thiadiazine-7-sulfonic acid amide (3211-40-3) → 6-chloro-3-cyclohexylmethyl-1,1-dioxo-1,2(4)-dihydro-1λ6-benzo[1,2,4]thiadiazine-7-sulfonic acid amide (106321-01-1)

Guidance literature:

With hydrogen; platinum(IV) oxide; In ethanol; at 100 ℃;

DOI:10.1021/jo01066a045

Reference yield:

chloraminophenamide (121-30-2) + 2-cyclohexylacetic anhydride (40608-15-9) → 6-chloro-3-cyclohexylmethyl-1,1-dioxo-1,2(4)-dihydro-1λ6-benzo[1,2,4]thiadiazine-7-sulfonic acid amide (106321-01-1)

Guidance literature:

In 1,4-dioxane; Heating;

DOI:10.1021/jo01066a045

Reference yield:

6-chloro-3-cyclohexylmethyl-1,1-dioxo-1,2(4)-dihydro-1λ6-benzo[1,2,4]thiadiazine-7-sulfonic acid amide (106321-01-1) → 6-chloro-3-cyclohexylmethyl-1,1-dioxo-1,2,3,4-tetrahydro-1λ6-benzo[1,2,4]thiadiazine-7-sulfonic acid amide (1824-67-5)

Guidance literature:

With sodium tetrahydroborate; aluminium trichloride; In tetrahydrofuran;

DOI:10.1021/jo01066a046

upstream raw materials:

chloraminophenamide

2-cyclohexylacetic anhydride

3-benzyl-6-chloro-1,1-dioxo-1,2(4)-dihydro-1λ⁶-benzo[1,2,4]thiadiazine-7-sulfonic acid amide

Downstream raw materials:

6-chloro-3-cyclohexylmethyl-1,1-dioxo-1,2,3,4-tetrahydro-1λ⁶-benzo[1,2,4]thiadiazine-7-sulfonic acid amide