3-(1-cyclopropyl-N-(cyclopropylmethylsulfonyl)methylsulfonamido)-2,6-difluorobenzoic acid

Base Information

Chemical Name:3-(1-cyclopropyl-N-(cyclopropylmethylsulfonyl)methylsulfonamido)-2,6-difluorobenzoic acid
CAS No.:1186194-04-6
Molecular Formula:C₁₅H₁₇F₂NO₆S₂
Molecular Weight:409.432
Hs Code.:

Synonyms:3-(1-cyclopropyl-N-(cyclopropylmethylsulfonyl)methylsulfonamido)-2,6-difluorobenzoic acid

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Chemical Property of 3-(1-cyclopropyl-N-(cyclopropylmethylsulfonyl)methylsulfonamido)-2,6-difluorobenzoic acid

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Technology Process of 3-(1-cyclopropyl-N-(cyclopropylmethylsulfonyl)methylsulfonamido)-2,6-difluorobenzoic acid

There total 1 articles about 3-(1-cyclopropyl-N-(cyclopropylmethylsulfonyl)methylsulfonamido)-2,6-difluorobenzoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 37.0%

: 83141-11-1
2,6-difluoro-3-aminobenzoic acid

: 114132-26-2
cyclopropylmethanesulfonyl chloride

: 1186194-04-6
3-(1-cyclopropyl-N-(cyclopropylmethylsulfonyl)methylsulfonamido)-2,6-difluorobenzoic acid

Guidance literature:: 2,6-difluoro-3-aminobenzoic acid; cyclopropylmethanesulfonyl chloride; With triethylamine; In dichloromethane; at 0 - 20 ℃;

With hydrogenchloride; In water; pH=1;

Reference yield: 51.0%

: 1186194-04-6
3-(1-cyclopropyl-N-(cyclopropylmethylsulfonyl)methylsulfonamido)-2,6-difluorobenzoic acid

: 1186194-03-5
3-(cyclopropylmethylsulfonamido)-2,6-difluorobenzoic acid

Guidance literature:: 3-(1-cyclopropyl-N-(cyclopropylmethylsulfonyl)methylsulfonamido)-2,6-difluorobenzoic acid; With sodium hydroxide; In tetrahydrofuran; methanol; at 20 ℃; for 1h;

With hydrogenchloride; In water; pH=1;