(4R)-4-Azido-1-Boc-D-proline benzyl ester

Base Information

Chemical Name:(4R)-4-Azido-1-Boc-D-proline benzyl ester
CAS No.:132622-97-0
Molecular Formula:C₁₇H₂₂N₄O₄
Molecular Weight:346.386
Hs Code.:
DSSTox Substance ID:DTXSID301130441

Synonyms:(4R)-4-Azido-1-Boc-D-proline benzyl ester;132622-97-0;2-O-benzyl 1-O-tert-butyl (2R,4R)-4-azidopyrrolidine-1,2-dicarboxylate;SCHEMBL20705287;NNBVAZYHYUBQCU-ZIAGYGMSSA-N;DTXSID301130441;F80494;(4R)-1-(tert-Butoxycarbonyl)-4-azido-D-proline Benzyl Ester;1-(1,1-Dimethylethyl) 2-(phenylmethyl) (2R,4R)-4-azido-1,2-pyrrolidinedicarboxylate

Suppliers and Price of (4R)-4-Azido-1-Boc-D-proline benzyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (4R)-4-Azido-1-Boc-D-proline benzyl ester

Chemical Property:

XLogP3:3.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:7
Exact Mass:346.16410520
Heavy Atom Count:25
Complexity:533

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(C)(C)OC(=O)N1CC(CC1C(=O)OCC2=CC=CC=C2)N=[N+]=[N-]
Isomeric SMILES:CC(C)(C)OC(=O)N1C[C@@H](C[C@@H]1C(=O)OCC2=CC=CC=C2)N=[N+]=[N-]

Technology Process of (4R)-4-Azido-1-Boc-D-proline benzyl ester

There total 6 articles about (4R)-4-Azido-1-Boc-D-proline benzyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: bromo benzyl ester

: 132622-93-6
(4S)-1-(tert-butoxycarbonyl)-4-bromo-D-proline benzyl ester

: 132622-97-0
2-benzyl 1-(tert-butyl) (2R,4R)-4-azidopyrrolidine-1,2-dicarboxylate

Guidance literature:: With sodium azide; In N,N-dimethyl-formamide;

Reference yield: 82.0%

: 132622-93-6
(4S)-1-(tert-butoxycarbonyl)-4-bromo-D-proline benzyl ester

: 132622-97-0
2-benzyl 1-(tert-butyl) (2R,4R)-4-azidopyrrolidine-1,2-dicarboxylate

Guidance literature:: With sodium azide; In N,N-dimethyl-formamide; at 55 ℃; for 24h;
DOI:10.1021/jm701214z

Reference yield:

: 481704-22-7
(2R,4S)-2-benzyl 1-tert-butyl 4-hydroxypyrrolidine-1,2-dicarboxylate

: 132622-97-0
2-benzyl 1-(tert-butyl) (2R,4R)-4-azidopyrrolidine-1,2-dicarboxylate

Guidance literature:: With diphenyl phosphoryl azide; triphenylphosphine; diethylazodicarboxylate; In tetrahydrofuran; toluene; at 0 - 20 ℃; for 24h; Inert atmosphere;