(1R,4R)-4-methyl-2-(phenylmethyl)-2,5-diazabicyclo<2.2.1>heptane dihydrobromide

Base Information

Chemical Name:(1R,4R)-4-methyl-2-(phenylmethyl)-2,5-diazabicyclo<2.2.1>heptane dihydrobromide
CAS No.:142824-29-1
Molecular Formula:2BrH*C₁₃H₁₈N₂
Molecular Weight:364.123
Hs Code.:

Synonyms:(1R,4R)-4-methyl-2-(phenylmethyl)-2,5-diazabicyclo<2.2.1>heptane dihydrobromide

Suppliers and Price of (1R,4R)-4-methyl-2-(phenylmethyl)-2,5-diazabicyclo<2.2.1>heptane dihydrobromide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (1R,4R)-4-methyl-2-(phenylmethyl)-2,5-diazabicyclo<2.2.1>heptane dihydrobromide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (1R,4R)-4-methyl-2-(phenylmethyl)-2,5-diazabicyclo<2.2.1>heptane dihydrobromide

There total 8 articles about (1R,4R)-4-methyl-2-(phenylmethyl)-2,5-diazabicyclo<2.2.1>heptane dihydrobromide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 142776-06-5
(1R,4R)-1-methyl-2-(p-toluenesulfonyl)-5-phenylmethyl-2,5-diazabicyclo<2.2.1>heptane

: 142824-29-1
(1R,4R)-4-methyl-2-(phenylmethyl)-2,5-diazabicyclo<2.2.1>heptane dihydrobromide

Guidance literature:: With hydrogen bromide; In acetic acid;
DOI:10.3987/COM-92-5984

Reference yield:

: 142776-08-7
(2S,4S)-1-(4-tolylsulfonyl)-4-<(4-tolylsulfonyl)oxy>-2-methylprolinol

: 142824-29-1
(1R,4R)-4-methyl-2-(phenylmethyl)-2,5-diazabicyclo<2.2.1>heptane dihydrobromide

Guidance literature:: Multi-step reaction with 3 steps

1: 29 percent

2: 30 percent / xylene / 12 h / 160 °C

3: 0.9 g / 33percent HBr, AcOH / 4 h / 70 - 80 °C

With hydrogen bromide; acetic acid; In xylene;
DOI:10.1021/jm00093a024

Reference yield:

: 142896-77-3
(2R,4S)-2-Methyl-1-(toluene-4-sulfonyl)-4-(toluene-4-sulfonyloxy)-pyrrolidine-2-carboxylic acid ethyl ester

: 142824-29-1
(1R,4R)-4-methyl-2-(phenylmethyl)-2,5-diazabicyclo<2.2.1>heptane dihydrobromide

Guidance literature:: Multi-step reaction with 4 steps

1: 61.6 percent / LiBH₄ / tetrahydrofuran / 2 h / 5 °C

2: 29 percent

3: 30 percent / xylene / 12 h / 160 °C

4: 0.9 g / 33percent HBr, AcOH / 4 h / 70 - 80 °C

With lithium borohydride; hydrogen bromide; acetic acid; In tetrahydrofuran; xylene;
DOI:10.1021/jm00093a024