142896-77-3

Upstream product

• 142824-30-4 (2R,4S)-4-Hydroxy-2-methyl-pyrrolidine-2-carboxylic acid ethyl ester; hydrochloride 
• 98-59-9 p-toluenesulfonyl chloride 
• 142824-25-7 (2S,4R)-4-hydroxy-2-methylproline ethyl ester 
• 142796-95-0 (2S,5R,7S)-2-tert-butyl-5-methyl-4-oxo-3-oxa-1-azabicyclo<3.3.0>oct-7-yl propionate 
• 142896-75-1 (2S,4R)-4-hydroxy-2-methylproline 

Downstream Products

• 142776-08-7 (2S,4S)-1-(4-tolylsulfonyl)-4-<(4-tolylsulfonyl)oxy>-2-methylprolinol 
• 142776-06-5 (1R,4R)-1-methyl-2-(p-toluenesulfonyl)-5-phenylmethyl-2,5-diazabicyclo<2.2.1>heptane 
• 142824-29-1 (1R,4R)-4-methyl-2-(phenylmethyl)-2,5-diazabicyclo<2.2.1>heptane dihydrobromide 
• 142896-78-4 C₂₇H₃₁NO₈S₃ 
• 142776-10-1 2,2,2-Trifluoro-1-((1R,4R)-1-methyl-2,5-diaza-bicyclo[2.2.1]hept-2-yl)-ethanone 
• 142776-09-8 1-((1R,4R)-5-Benzyl-1-methyl-2,5-diaza-bicyclo[2.2.1]hept-2-yl)-2,2,2-trifluoro-ethanone 
• 142776-11-2 7-((1R,4R)-5-Benzyl-1-methyl-2,5-diaza-bicyclo[2.2.1]hept-2-yl)-1-tert-butyl-6-fluoro-4-oxo-1,4-dihydro-[1,8]naphthyridine-3-carboxylic acid ethyl ester 

Relevant academic research and scientific papers

Fluoronaphthyridines as Antibacterial Agents. 6. Synthesis and Structure-Activity Relationships of New Chiral 7-(1-, 3-, 4-, and 6-Methyl-2,5-diazabicycloheptan-2-yl)naphthyridine Analogues of 7-heptan-2-yl>-1-(1,1-d

A series of novel chiral 7-(1-, 3-, 4-, and 6-methylheptan-2-yl>-substituted naphthyridines has been prepared with the aim of obtaining good in vitro and in vivo antibacterial agents with a decrease of the pseudoallergic t

PREPARATION OF (1R,4R)-1-METHYL-2-(p-TOLUENESULFONYL)-5-PHENYLMETHYL-2,5-DIAZABICYCLOHEPTANE, INTERMEDIATE IN A SYNTHESIS OF NEW NAPHTHYRIDONES

An efficient chiral synthesis of the (1R,4R)-1-methyl-2-(p-toluenesulfonyl)-5-phenylmethyl-2,5-diazabicycloheptane (2b) was performed using trans-4-hydroxy-L-proline as starting material.This bridged piperazine was used in the preparation of new na