5-[2-Chloro-5-(trifluoromethyl)phenyl]-2-furoic acid

Base Information

Chemical Name:5-[2-Chloro-5-(trifluoromethyl)phenyl]-2-furoic acid
CAS No.:302911-88-2
Molecular Formula:C12H6 Cl F3 O3
Molecular Weight:290.626
Hs Code.:2932190090
European Community (EC) Number:685-907-5
DSSTox Substance ID:DTXSID00350259
Wikidata:Q82126103
Mol file:302911-88-2.mol

Synonyms:302911-88-2;5-[2-Chloro-5-(trifluoromethyl)phenyl]-2-furoic acid;5-[2-chloro-5-(trifluoromethyl)phenyl]furan-2-carboxylic Acid;5-(2-Chloro-5-(trifluoromethyl)phenyl)furan-2-carboxylic acid;5-(2-CHLORO-5-(TRIFLUOROMETHYL)PHENYL)-&;5-(2-chloro-5-trifluoromethylphenyl)furan-2-carboxylic acid;SCHEMBL4946316;DTXSID00350259;SSIFVNBQAZVYCS-UHFFFAOYSA-N;STL376948;AKOS000109302;CCG-253676;SB61065;BB 0244860;CS-0318165;J-017862;5-[2-chloro-5-(trifluoromethyl)-phenyl]-2-furoic acid;5-[2-Chloro-5-(trifluoromethyl)phenyl]-2-furoic acid, 96%;5-(2-Chloro-5-trifluoromethyl-phenyl)-furan-2- carboxylic acid

Suppliers and Price of 5-[2-Chloro-5-(trifluoromethyl)phenyl]-2-furoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Sigma-Aldrich
5-[2-Chloro-5-(trifluoromethyl)phenyl]-2-furoic acid 96%
5g
$ 174.00

Sigma-Aldrich
5-[2-Chloro-5-(trifluoromethyl)phenyl]-2-furoic acid 96%
1g
$ 48.20

Biosynth Carbosynth
5-[2-Chloro-5-(trifluoromethyl)phenyl]-2-furancarboxylic acid
1 g
$ 100.00

Biosynth Carbosynth
5-[2-Chloro-5-(trifluoromethyl)phenyl]-2-furancarboxylic acid
500 mg
$ 60.00

Biosynth Carbosynth
5-[2-Chloro-5-(trifluoromethyl)phenyl]-2-furancarboxylic acid
250 mg
$ 45.00

Biosynth Carbosynth
5-[2-Chloro-5-(trifluoromethyl)phenyl]-2-furancarboxylic acid
5 g
$ 350.00

Biosynth Carbosynth
5-[2-Chloro-5-(trifluoromethyl)phenyl]-2-furancarboxylic acid
2 g
$ 180.00

American Custom Chemicals Corporation
5-[2-CHLORO-5-(TRIFLUOROMETHYL)PHENYL]-2-FUROIC ACID 95.00%
500MG
$ 711.89

AK Scientific
5-[2-Chloro-5-(trifluoromethyl)phenyl]-2-furoic acid
1g
$ 114.00

Total 6 raw suppliers

Chemical Property of 5-[2-Chloro-5-(trifluoromethyl)phenyl]-2-furoic acid

Chemical Property:

Vapor Pressure:2.66E-06mmHg at 25°C
Melting Point:215-219 °C (dec.)(lit.)
Refractive Index:1.525
Boiling Point:375.4°C at 760 mmHg
Flash Point:180.8°C
PSA：50.44000
Density:1.486g/cm³
LogP:4.31700
XLogP3:4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:2
Exact Mass:289.9957562
Heavy Atom Count:19
Complexity:348

Purity/Quality:

98% ^*data from raw suppliers

5-[2-Chloro-5-(trifluoromethyl)phenyl]-2-furoic acid 96% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xi
Statements: 36/37/38
Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Canonical SMILES:C1=CC(=C(C=C1C(F)(F)F)C2=CC=C(O2)C(=O)O)Cl

Technology Process of 5-[2-Chloro-5-(trifluoromethyl)phenyl]-2-furoic acid

There total 2 articles about 5-[2-Chloro-5-(trifluoromethyl)phenyl]-2-furoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 773874-53-6
5-(2-chloro-5-trifluoromethylphenyl)furan-2-carboxylic acid

: 302911-88-2
5-(2-chloro-5-trifluoromethylphenyl)furan-2-carboxylic acid

Guidance literature:: With potassium hydroxide; In ethanol; for 0.5h; Reflux;
DOI:10.1134/S1070428009040125

Reference yield:

: 88-14-2
2-furanoic acid

: 121-50-6
3-amino-4-chlorobenzotrifluoride

: 302911-88-2
5-(2-chloro-5-trifluoromethylphenyl)furan-2-carboxylic acid

Guidance literature:: 3-amino-4-chlorobenzotrifluoride; With hydrogenchloride; sodium nitrite; at 0 - 5 ℃;

2-furanoic acid; With copper dichloride; In water; at 20 ℃; for 4h; Further stages.;
DOI:10.1080/10426500601096435