4-(4-chloro-phenyl)-N-hydroxy-6-trifluoromethyl-pyrimidine-2-carboxamidine

Base Information

Chemical Name:4-(4-chloro-phenyl)-N-hydroxy-6-trifluoromethyl-pyrimidine-2-carboxamidine
CAS No.:951232-23-8
Molecular Formula:C₁₂H₈ClF₃N₄O
Molecular Weight:316.67
Hs Code.:

Synonyms:4-(4-chloro-phenyl)-N-hydroxy-6-trifluoromethyl-pyrimidine-2-carboxamidine

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Chemical Property of 4-(4-chloro-phenyl)-N-hydroxy-6-trifluoromethyl-pyrimidine-2-carboxamidine

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Technology Process of 4-(4-chloro-phenyl)-N-hydroxy-6-trifluoromethyl-pyrimidine-2-carboxamidine

There total 1 articles about 4-(4-chloro-phenyl)-N-hydroxy-6-trifluoromethyl-pyrimidine-2-carboxamidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 951232-08-9
4-(4-chloro-phenyl)-6-trifluoromethyl-pyrimidine-2-carbonitrile

: 951232-23-8
4-(4-chloro-phenyl)-N-hydroxy-6-trifluoromethyl-pyrimidine-2-carboxamidine

Guidance literature:: With hydroxylamine hydrochloride; sodium carbonate; In ethanol; water; for 2h; Heating / reflux;

Reference yield: 43.0%

: 951232-23-8
4-(4-chloro-phenyl)-N-hydroxy-6-trifluoromethyl-pyrimidine-2-carboxamidine

: 636-76-0
3-sulfamoylbenzoic acid

: 3-{3-[4-(4-Chloro-phenyl)-6-trifluoromethyl-pyrimidin-2-yl]-[1,2,4]oxadiazol-5-yl}-benzenesulfonamide

Guidance literature:: 3-sulfamoylbenzoic acid; With 1,1'-carbonyldiimidazole; at 20 ℃; for 2h;

4-(4-chloro-phenyl)-N-hydroxy-6-trifluoromethyl-pyrimidine-2-carboxamidine; at 80 ℃; for 15h;

With acetic acid; for 4h; Heating / reflux;