methyl 2,6-anhydro-3-O-benzoyl-5-O-tert-butyldimethylsilyl-3-C-hydroxymethyl-α-D-arabinofuranoside

Base Information

Chemical Name:methyl 2,6-anhydro-3-O-benzoyl-5-O-tert-butyldimethylsilyl-3-C-hydroxymethyl-α-D-arabinofuranoside
CAS No.:440359-36-4
Molecular Formula:C₂₀H₃₀O₆Si
Molecular Weight:394.54
Hs Code.:

Synonyms:methyl 2,6-anhydro-3-O-benzoyl-5-O-tert-butyldimethylsilyl-3-C-hydroxymethyl-α-D-arabinofuranoside

Suppliers and Price of methyl 2,6-anhydro-3-O-benzoyl-5-O-tert-butyldimethylsilyl-3-C-hydroxymethyl-α-D-arabinofuranoside

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of methyl 2,6-anhydro-3-O-benzoyl-5-O-tert-butyldimethylsilyl-3-C-hydroxymethyl-α-D-arabinofuranoside

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of methyl 2,6-anhydro-3-O-benzoyl-5-O-tert-butyldimethylsilyl-3-C-hydroxymethyl-α-D-arabinofuranoside

There total 13 articles about methyl 2,6-anhydro-3-O-benzoyl-5-O-tert-butyldimethylsilyl-3-C-hydroxymethyl-α-D-arabinofuranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1053626-56-4
Benzoic acid (2R,3S,4S,5S)-3-bromomethyl-2-(tert-butyl-dimethyl-silanyloxymethyl)-4-hydroxy-5-methoxy-tetrahydro-furan-3-yl ester

: 440359-36-4
methyl 2,6-anhydro-3-O-benzoyl-5-O-tert-butyldimethylsilyl-3-C-hydroxymethyl-α-D-arabinofuranoside

Guidance literature:: With potassium carbonate; In N,N-dimethyl-formamide; at 20 ℃; for 36h;
DOI:10.1021/jo011127p

Reference yield:

: 26532-10-5
methyl 2,3-anhydro-α-D-lyxofuranoside

: 440359-36-4
methyl 2,6-anhydro-3-O-benzoyl-5-O-tert-butyldimethylsilyl-3-C-hydroxymethyl-α-D-arabinofuranoside

Guidance literature:: Multi-step reaction with 11 steps

1: 83 percent / phenylmethanol / 3 h / 120 °C

2: 74 percent / pyridine / CH₂Cl₂ / 4 h / -78 - 0 °C

3: 94 percent / H₂ / Pd(OH)2 / methanol / 72 h / 20 °C

4: pyridinium chlorochromate; sodium acetate; molecular sieves 4 Angstroem / CH₂Cl₂ / 8 h / 20 °C

5: 273 mg / tetrahydrofuran / 13 h / 70 °C

6: RuCl₃*H₂O; sodium periodate / ethyl acetate; acetonitrile; H₂O / 0.5 h / 0 °C

7: 569 mg / p-TsOH / CH₂Cl₂ / 18 h / 20 - 40 °C

8: 86 percent / HF / tetrahydrofuran; pyridine / 4 h / 20 °C

9: 87 percent / imidazole / dimethylformamide / 4 h / 0 °C

10: barium carbonate; N-bromosuccinimide / CCl₄ / 3 h / Heating

11: 15 mg / potassium carbonate / dimethylformamide / 36 h / 20 °C

With pyridine; 1H-imidazole; ruthenium trichloride; sodium periodate; N-Bromosuccinimide; 4 A molecular sieve; hydrogen fluoride; hydrogen; sodium acetate; potassium carbonate; toluene-4-sulfonic acid; barium carbonate; pyridinium chlorochromate; palladium dihydroxide; In tetrahydrofuran; pyridine; methanol; tetrachloromethane; dichloromethane; water; ethyl acetate; N,N-dimethyl-formamide; acetonitrile; benzyl alcohol;
DOI:10.1021/jo011127p

Reference yield:

: 440359-26-2
methyl 3-O-benzyl-2,5-bis-O-di-tert-butylsilyl-α-D-arabinofuranoside

: 440359-36-4
methyl 2,6-anhydro-3-O-benzoyl-5-O-tert-butyldimethylsilyl-3-C-hydroxymethyl-α-D-arabinofuranoside

Guidance literature:: Multi-step reaction with 9 steps

1: 94 percent / H₂ / Pd(OH)2 / methanol / 72 h / 20 °C

2: pyridinium chlorochromate; sodium acetate; molecular sieves 4 Angstroem / CH₂Cl₂ / 8 h / 20 °C

3: 273 mg / tetrahydrofuran / 13 h / 70 °C

4: RuCl₃*H₂O; sodium periodate / ethyl acetate; acetonitrile; H₂O / 0.5 h / 0 °C

5: 569 mg / p-TsOH / CH₂Cl₂ / 18 h / 20 - 40 °C

6: 86 percent / HF / tetrahydrofuran; pyridine / 4 h / 20 °C

7: 87 percent / imidazole / dimethylformamide / 4 h / 0 °C

8: barium carbonate; N-bromosuccinimide / CCl₄ / 3 h / Heating

9: 15 mg / potassium carbonate / dimethylformamide / 36 h / 20 °C

With 1H-imidazole; ruthenium trichloride; sodium periodate; N-Bromosuccinimide; 4 A molecular sieve; hydrogen fluoride; hydrogen; sodium acetate; potassium carbonate; toluene-4-sulfonic acid; barium carbonate; pyridinium chlorochromate; palladium dihydroxide; In tetrahydrofuran; pyridine; methanol; tetrachloromethane; dichloromethane; water; ethyl acetate; N,N-dimethyl-formamide; acetonitrile;
DOI:10.1021/jo011127p