2-[4-(benzyloxy)phenyl]-N-[(2,2-dimethyl-1,3-dioxolan-4-yl)methyl]-3-hydroxy-2-methylpropanamide

Base Information

Chemical Name:2-[4-(benzyloxy)phenyl]-N-[(2,2-dimethyl-1,3-dioxolan-4-yl)methyl]-3-hydroxy-2-methylpropanamide
CAS No.:864657-76-1
Molecular Formula:C₂₃H₂₉NO₅
Molecular Weight:399.487
Hs Code.:

Synonyms:2-[4-(benzyloxy)phenyl]-N-[(2,2-dimethyl-1,3-dioxolan-4-yl)methyl]-3-hydroxy-2-methylpropanamide

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Chemical Property of 2-[4-(benzyloxy)phenyl]-N-[(2,2-dimethyl-1,3-dioxolan-4-yl)methyl]-3-hydroxy-2-methylpropanamide

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Technology Process of 2-[4-(benzyloxy)phenyl]-N-[(2,2-dimethyl-1,3-dioxolan-4-yl)methyl]-3-hydroxy-2-methylpropanamide

There total 1 articles about 2-[4-(benzyloxy)phenyl]-N-[(2,2-dimethyl-1,3-dioxolan-4-yl)methyl]-3-hydroxy-2-methylpropanamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 864657-75-0
2-[4-(benzyloxy)phenyl]-3-hydroxy-2-methylpropanoic acid

: 22195-47-7,96894-67-6
4-aminomethyl-2,2-dimethyl[1,3]dioxolane

: 864657-76-1
2-[4-(benzyloxy)phenyl]-N-[(2,2-dimethyl-1,3-dioxolan-4-yl)methyl]-3-hydroxy-2-methylpropanamide

Guidance literature:: With O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine; In DMF (N,N-dimethyl-formamide); at 20 ℃; for 1h;

Reference yield:

: 864657-76-1
2-[4-(benzyloxy)phenyl]-N-[(2,2-dimethyl-1,3-dioxolan-4-yl)methyl]-3-hydroxy-2-methylpropanamide

: 864657-77-2
3-[4-(benzyloxy)phenyl]-1-[(2,2-dimethyl-1,3-dioxolan-4-yl)methyl]-3-methylazetidin-2-one

Guidance literature:: 2-[4-(benzyloxy)phenyl]-N-[(2,2-dimethyl-1,3-dioxolan-4-yl)methyl]-3-hydroxy-2-methylpropanamide; With methanesulfonyl chloride; In pyridine; at 20 ℃; for 0.025h;

With potassium carbonate; In acetone; at 20 ℃; for 120h; Heating / reflux;