Carbamic acid, [1,1-bis(hydroxymethyl)propyl]-, 1,1-dimethylethyl ester (9CI)

Base Information

Chemical Name:Carbamic acid, [1,1-bis(hydroxymethyl)propyl]-, 1,1-dimethylethyl ester (9CI)
CAS No.:391678-52-7
Molecular Formula:C10H21 N O4
Molecular Weight:219.281
Hs Code.:
Mol file:391678-52-7.mol

Synonyms:Carbamicacid, [1,1-bis(hydroxymethyl)propyl]-, 1,1-dimethylethyl ester (9CI); [1,1-Bis(hydroxymethyl)propyl]carbamicacid tert-butyl ester; [1-Ethyl-2-hydroxy-1-(hydroxymethyl)ethyl]carbamic acidtert-butyl ester

Suppliers and Price of Carbamic acid, [1,1-bis(hydroxymethyl)propyl]-, 1,1-dimethylethyl ester (9CI)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
BOC-2-AMINO-2-ETHYL-1,3-PROPANEDIOL 95.00%
5MG
$ 498.08

Total 1 raw suppliers

Chemical Property of Carbamic acid, [1,1-bis(hydroxymethyl)propyl]-, 1,1-dimethylethyl ester (9CI)

Chemical Property:

PSA：82.28000
LogP:0.84890

Purity/Quality:: BOC-2-AMINO-2-ETHYL-1,3-PROPANEDIOL 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of Carbamic acid, [1,1-bis(hydroxymethyl)propyl]-, 1,1-dimethylethyl ester (9CI)

There total 1 articles about Carbamic acid, [1,1-bis(hydroxymethyl)propyl]-, 1,1-dimethylethyl ester (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

: 24424-99-5
di-tert-butyl dicarbonate

: 115-70-8
2-ethyl-2-amino-propane-1,3-diol

: 391678-52-7
2-((tert-butoxycarbonyl)amino)-2-ethyl-1,3-propanediol

Guidance literature:: With triethylamine; In dichloromethane; at 20 ℃; for 20h;
DOI:10.1021/ol063063g

Reference yield: 93.0%

: 391678-52-7
2-((tert-butoxycarbonyl)amino)-2-ethyl-1,3-propanediol

: 990-91-0
dibenzyl [[bis(benzyloxy)phosphoryl]oxy]phosphonate

: 1401995-59-2
2-(tert-butoxycarbonyl)amino-2-ethyl-3-hydroxylpropyl dibenzyl phosphate

Guidance literature:: With titanium(IV) tetrabutoxide; N-ethyl-N,N-diisopropylamine; In dichloromethane; at 20 ℃; for 16h; Inert atmosphere;
DOI:10.1016/j.tet.2012.08.070

Reference yield:

: 391678-52-7
2-((tert-butoxycarbonyl)amino)-2-ethyl-1,3-propanediol

: 990-91-0
dibenzyl [[bis(benzyloxy)phosphoryl]oxy]phosphonate

: tert-butyl (1-((bis(benzyloxy)phosphoryl)oxy)-2-(hydroxymethyl)butan-2-yl)carbamate

: (R)-tert-butyl (1-((bis(benzyloxy)phosphoryl)oxy)-2-(hydroxymethyl)butan-2-yl)carbamate

Guidance literature:: With titanium(IV) isopropylate; (R)-1,1'-Bi-2-naphthol; N-ethyl-N,N-diisopropylamine; In dichloromethane; at 0 ℃; for 16h; Overall yield = 94 percent; Overall yield = 169 mg; enantioselective reaction; Inert atmosphere;
DOI:10.1021/acs.joc.1c00414