4-[5-(ethoxycarbonyl)-1H-pyrrol-3-yl]-4-oxobutanoic acid

Base Information

Chemical Name:4-[5-(ethoxycarbonyl)-1H-pyrrol-3-yl]-4-oxobutanoic acid
CAS No.:119647-71-1
Molecular Formula:C₁₁H₁₃NO₅
Molecular Weight:239.228
Hs Code.:

Synonyms:4-[5-(ethoxycarbonyl)-1H-pyrrol-3-yl]-4-oxobutanoic acid

Suppliers and Price of 4-[5-(ethoxycarbonyl)-1H-pyrrol-3-yl]-4-oxobutanoic acid

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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AK Scientific
4-[5-(Ethoxycarbonyl)-1H-pyrrol-3-yl]-4-oxobutanoicacid
1g
$ 897.00

Total 1 raw suppliers

Chemical Property of 4-[5-(ethoxycarbonyl)-1H-pyrrol-3-yl]-4-oxobutanoic acid

Chemical Property:

Purity/Quality:: 4-[5-(Ethoxycarbonyl)-1H-pyrrol-3-yl]-4-oxobutanoicacid ^*data from reagent suppliers

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Technology Process of 4-[5-(ethoxycarbonyl)-1H-pyrrol-3-yl]-4-oxobutanoic acid

There total 1 articles about 4-[5-(ethoxycarbonyl)-1H-pyrrol-3-yl]-4-oxobutanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 108-30-5
succinic acid anhydride

: 2199-43-1
ethyl 1H-pyrrole-2-carboxylate

: 119647-71-1
4-[5-(ethoxycarbonyl)-1H-pyrrol-3-yl]-4-oxobutanoic acid

Guidance literature:: With aluminum (III) chloride; In 1,2-dichloro-ethane; at 20 ℃; for 3.33333h;

Reference yield: 30.0%

: 119647-71-1
4-[5-(ethoxycarbonyl)-1H-pyrrol-3-yl]-4-oxobutanoic acid

: 119647-72-2
4-[5-(ethoxycarbonyl)-1H-pyrrol-3-yl]butanoic Acid

Guidance literature:: With triethylsilane; trifluoroacetic acid; at 20 ℃; for 8h;

Reference yield:

: 119647-71-1
4-[5-(ethoxycarbonyl)-1H-pyrrol-3-yl]-4-oxobutanoic acid

: 1-Benzyl-7-cyano-1H-indole-2-carboxylic acid ethyl ester

Guidance literature:: Multi-step reaction with 5 steps

1: 42 g / trifluoroacetic acid, H₂ / 10percent Pd/C / acetic acid / 2585.7 Torr

2: 82 percent / trifluoroacetic anhydride / trifluoroacetic acid / 3 h

3: 1.) zinc iodide, 2.) phosphorus oxychloride / 1.) benzene, 4 h, 2.) pyridine, 80 deg C, 3 h

4: DDQ / dioxane / 3 h

5: 1.) NaH / 1.) DMF, 1 h, 2.) DMF, overnight

With hydrogen; sodium hydride; trifluoroacetic acid; trifluoroacetic anhydride; 2,3-dicyano-5,6-dichloro-p-benzoquinone; zinc(II) iodide; trichlorophosphate; palladium on activated charcoal; In 1,4-dioxane; acetic acid; trifluoroacetic acid;
DOI:10.1021/jm00001a014