N-(2-methoxy-6-pentadecylbenzyl)-1-phenylmethanesulfonamide

Base Information

• Chemical Name: N-(2-methoxy-6-pentadecylbenzyl)-1-phenylmethanesulfonamide
• CAS No.: 1375801-06-1
• Molecular Formula: C₃₀H₄₇NO₃S
• Molecular Weight: 501.774
• Mol file: 1375801-06-1.mol

Synonyms:N-(2-methoxy-6-pentadecylbenzyl)-1-phenylmethanesulfonamide

Chemical Property of N-(2-methoxy-6-pentadecylbenzyl)-1-phenylmethanesulfonamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-(2-methoxy-6-pentadecylbenzyl)-1-phenylmethanesulfonamide

There total 6 articles about N-(2-methoxy-6-pentadecylbenzyl)-1-phenylmethanesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 64.6%

2-methoxy-6-pentadecylphenylmethanamine (1363400-50-3) + benzenesulfonyl chloride (1939-99-7) → N-(2-methoxy-6-pentadecylbenzyl)-1-phenylmethanesulfonamide (1375801-06-1)

Guidance literature:

With triethylamine; In dichloromethane; at 0 - 20 ℃; for 2h;

DOI:10.2174/157017812800233660

Reference yield:

2-(azidomethyl)-1-methoxy-3-pentadecylbenzene (1375800-98-8) → N-(2-methoxy-6-pentadecylbenzyl)-1-phenylmethanesulfonamide (1375801-06-1)

Guidance literature:

Multi-step reaction with 2 steps

1: palladium 10% on activated carbon; hydrogen / ethanol / 2 h / 3102.97 Torr / Inert atmosphere

2: triethylamine / dichloromethane / 2 h / 0 - 20 °C

With palladium 10% on activated carbon; hydrogen; triethylamine; In ethanol; dichloromethane;

DOI:10.2174/157017812800233660

Reference yield:

methanesulfonic acid 2-methoxy-6-pentadecyl-benzyl ester (1361955-58-9) → N-(2-methoxy-6-pentadecylbenzyl)-1-phenylmethanesulfonamide (1375801-06-1)

Guidance literature:

Multi-step reaction with 3 steps

1: sodium azide / N,N-dimethyl-formamide / 2 h / 100 °C

2: palladium 10% on activated carbon; hydrogen / ethanol / 2 h / 3102.97 Torr / Inert atmosphere

3: triethylamine / dichloromethane / 2 h / 0 - 20 °C

With sodium azide; palladium 10% on activated carbon; hydrogen; triethylamine; In ethanol; dichloromethane; N,N-dimethyl-formamide;

DOI:10.2174/157017812800233660

upstream raw materials:

2-methoxy-6-pentadecylphenylmethanamine

benzenesulfonyl chloride

methanesulfonic acid 2-methoxy-6-pentadecyl-benzyl ester

2-(azidomethyl)-1-methoxy-3-pentadecylbenzene