2-(azidomethyl)-1-methoxy-3-pentadecylbenzene

Base Information

• Chemical Name: 2-(azidomethyl)-1-methoxy-3-pentadecylbenzene
• CAS No.: 1375800-98-8
• Molecular Formula: C₂₃H₃₉N₃O
• Molecular Weight: 373.582
• Mol file: 1375800-98-8.mol

Synonyms:2-(azidomethyl)-1-methoxy-3-pentadecylbenzene

Chemical Property of 2-(azidomethyl)-1-methoxy-3-pentadecylbenzene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-(azidomethyl)-1-methoxy-3-pentadecylbenzene

There total 6 articles about 2-(azidomethyl)-1-methoxy-3-pentadecylbenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.4%

methanesulfonic acid 2-methoxy-6-pentadecyl-benzyl ester (1361955-58-9) → 2-(azidomethyl)-1-methoxy-3-pentadecylbenzene (1375800-98-8)

Guidance literature:

With sodium azide; In N,N-dimethyl-formamide; at 100 ℃; for 2h;

DOI:10.2174/157017812800233660

Reference yield: 90.0%

2-(bromomethyl)-1-methoxy-3-pentadecylbenzene → 2-(azidomethyl)-1-methoxy-3-pentadecylbenzene (1375800-98-8)

Guidance literature:

With sodium azide; In N,N-dimethyl-formamide; at 90 ℃; for 1h;

DOI:10.14233/ajchem.2016.19310

Reference yield:

(2-methoxy-6-(pentadecyl)phenyl)methanol (79688-40-7) → 2-(azidomethyl)-1-methoxy-3-pentadecylbenzene (1375800-98-8)

Guidance literature:

Multi-step reaction with 2 steps

1: triethylamine / dichloromethane / 3.25 h / 0 - 20 °C

2: sodium azide / N,N-dimethyl-formamide / 2 h / 100 °C

With sodium azide; triethylamine; In dichloromethane; N,N-dimethyl-formamide;

DOI:10.2174/157017812800233660

upstream raw materials:

methanesulfonic acid 2-methoxy-6-pentadecyl-benzyl ester

6-Pentadecylsalicylic Acid

2-methoxy-6-pentadecyl-benzoic acid methyl ester

(2-methoxy-6-(pentadecyl)phenyl)methanol

Downstream raw materials:

2-methoxy-6-pentadecylphenylmethanamine

N-(2-methoxy-6-pentadecylbenzyl)-1-phenylmethanesulfonamide

N-(2-methoxy-6-pentadecylbenzyl)naphthalene-2-sulfonamide

N-(2-methoxy-6-pentadecylbenzyl)thiophene-2-sulfonamide

Refernces

• 1、 Reddy, N. Subhakara,Rao, A. Srinivas,Chari, M. Adharvana,Kumar, V. Ravi,Jyothy,Himabindu. "Synthesis and antibacterial activity of sulfonamide derivatives of anacardicacid mixture isolated from a natural product Cashew Nut Shell Liquid (CNSL)". experimental part. p. 287 - 293. Retrieved 2012/07/31.