cis 1,3-Dibenzyl-4-(1'-methylthiothiocarbonyloxypentyl)-5-benzyloxymethylimidazolidin-2-one

Base Information

• Chemical Name: cis 1,3-Dibenzyl-4-(1'-methylthiothiocarbonyloxypentyl)-5-benzyloxymethylimidazolidin-2-one
• CAS No.: 133709-90-7
• Molecular Formula: C₃₂H₃₈N₂O₃S₂
• Molecular Weight: 562.797
• Mol file: 133709-90-7.mol

Synonyms:cis 1,3-Dibenzyl-4-(1'-methylthiothiocarbonyloxypentyl)-5-benzyloxymethylimidazolidin-2-one

Chemical Property of cis 1,3-Dibenzyl-4-(1'-methylthiothiocarbonyloxypentyl)-5-benzyloxymethylimidazolidin-2-one

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of cis 1,3-Dibenzyl-4-(1'-methylthiothiocarbonyloxypentyl)-5-benzyloxymethylimidazolidin-2-one

There total 4 articles about cis 1,3-Dibenzyl-4-(1'-methylthiothiocarbonyloxypentyl)-5-benzyloxymethylimidazolidin-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(3aS,6aR)-1,3-dibenzyltetrahydro-1H-furo[3,4-d]imidazole-2,4-dione (28092-62-8) → cis 1,3-Dibenzyl-4-(1'-methylthiothiocarbonyloxypentyl)-5-benzyloxymethylimidazolidin-2-one (133709-90-7)

Guidance literature:

Multi-step reaction with 4 steps

1: 1) Mg, I₂ / 1)THF, reflux, 1 h, 2) toluene, reflux, 1.5 h

2: 95 percent / NaBH₄ / ethanol / 3 h / 0 °C

3: 1) NaH / 1) THF, r.t., 15 min, 2) r.t., overnight

4: imidazole, NaH

With 1H-imidazole; sodium tetrahydroborate; iodine; sodium hydride; magnesium; In ethanol;

Reference yield:

cis 4-Butyl-1,3-dibenzyl-4-hydroxy-2,3,3a,4,6,6a-hexahydrofuro<3,4-d>imidazol-2-one (133709-67-8,133775-11-8) → cis 1,3-Dibenzyl-4-(1'-methylthiothiocarbonyloxypentyl)-5-benzyloxymethylimidazolidin-2-one (133709-90-7)

Guidance literature:

Multi-step reaction with 3 steps

1: 95 percent / NaBH₄ / ethanol / 3 h / 0 °C

2: 1) NaH / 1) THF, r.t., 15 min, 2) r.t., overnight

3: imidazole, NaH

With 1H-imidazole; sodium tetrahydroborate; sodium hydride; In ethanol;

Reference yield:

cis 1,3-Dibenzyl 4-(1'-hydroxypentyl)-5-hydroxymethylimidazolidin-2-one (133709-68-9) → cis 1,3-Dibenzyl-4-(1'-methylthiothiocarbonyloxypentyl)-5-benzyloxymethylimidazolidin-2-one (133709-90-7)

Guidance literature:

Multi-step reaction with 2 steps

1: 1) NaH / 1) THF, r.t., 15 min, 2) r.t., overnight

2: imidazole, NaH

With 1H-imidazole; sodium hydride;

upstream raw materials:

carbon disulfide

cis 1,3-Dibenzyl-4-(1'-hydroxypentyl)-5-benzyloxymethyl-imidazolidin-2-one

methyl iodide

(3aS,6aR)-1,3-dibenzyltetrahydro-1H-furo[3,4-d]imidazole-2,4-dione

Downstream raw materials:

cis 1,3-Dibenzyl-4-pentyl-5-benzyloxymethylimidazolidin-2-one