(4-(trifluoromethyl)benzyl) 3β-hydroxy-olean-12-en-30-oate

Base Information

• Chemical Name: (4-(trifluoromethyl)benzyl) 3β-hydroxy-olean-12-en-30-oate
• CAS No.: 1375692-79-7
• Molecular Formula: C₃₈H₅₃F₃O₃
• Molecular Weight: 614.832
• Mol file: 1375692-79-7.mol

Synonyms:(4-(trifluoromethyl)benzyl) 3β-hydroxy-olean-12-en-30-oate

Chemical Property of (4-(trifluoromethyl)benzyl) 3β-hydroxy-olean-12-en-30-oate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (4-(trifluoromethyl)benzyl) 3β-hydroxy-olean-12-en-30-oate

There total 1 articles about (4-(trifluoromethyl)benzyl) 3β-hydroxy-olean-12-en-30-oate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.7%

11-deoxyglycyrrhetinic acid (6894-46-8,14796-53-3,17956-00-2,76035-62-6,564-16-9) + 4-bromomethyltrifluoromethylbenzene (402-49-3) → (4-(trifluoromethyl)benzyl) 3β-hydroxy-olean-12-en-30-oate (1375692-79-7)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 20 ℃;

DOI:10.1016/j.bmcl.2012.03.081

Reference yield: 78.6%

3,4,5-trimethoxycinnamic acid (90-50-6) + (4-(trifluoromethyl)benzyl) 3β-hydroxy-olean-12-en-30-oate (1375692-79-7) → (4-(trifluoromethyl)benzyl) 3-O-(3,4,5-trimethoxycinnamoyl)-olean-12-en-30-oate

Guidance literature:

With dmap; dicyclohexyl-carbodiimide; In dichloromethane; at 0 - 20 ℃; Reflux;

DOI:10.1016/j.bmcl.2012.03.081

Reference yield: 75.2%

3-methoxycinnamic acid (6099-04-3,17570-26-2) + (4-(trifluoromethyl)benzyl) 3β-hydroxy-olean-12-en-30-oate (1375692-79-7) → (4-(trifluoromethyl)benzyl) 3-O-(3-methoxycinnamoyl)-olean-12-en-30-oate

Guidance literature:

With dmap; dicyclohexyl-carbodiimide; In dichloromethane; at 0 - 20 ℃; Reflux;

DOI:10.1016/j.bmcl.2012.03.081

upstream raw materials:

11-deoxyglycyrrhetinic acid

4-bromomethyltrifluoromethylbenzene

Downstream raw materials:

(4-(trifluoromethyl)benzyl) 3-O-(4-oxo-4H-1-benzopyran-2-carbonyl)-olean-12-en-30-oate