2-fluoro-4-[5-(tert-butyldiphenylsilanyloxy)-pentylselanyl]-phenyloxyacetic acid

Base Information

Chemical Name:2-fluoro-4-[5-(tert-butyldiphenylsilanyloxy)-pentylselanyl]-phenyloxyacetic acid
CAS No.:831223-29-1
Molecular Formula:C₂₉H₃₅FO₄SeSi
Molecular Weight:573.638
Hs Code.:

Synonyms:2-fluoro-4-[5-(tert-butyldiphenylsilanyloxy)-pentylselanyl]-phenyloxyacetic acid

Suppliers and Price of 2-fluoro-4-[5-(tert-butyldiphenylsilanyloxy)-pentylselanyl]-phenyloxyacetic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 2-fluoro-4-[5-(tert-butyldiphenylsilanyloxy)-pentylselanyl]-phenyloxyacetic acid

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2-fluoro-4-[5-(tert-butyldiphenylsilanyloxy)-pentylselanyl]-phenyloxyacetic acid

There total 4 articles about 2-fluoro-4-[5-(tert-butyldiphenylsilanyloxy)-pentylselanyl]-phenyloxyacetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 831223-28-0
ethyl 2-fluoro-4-[5-(tert-butyldiphenylsilanyloxy)-pentylselanyl]-phenyloxyacetate

: 831223-29-1
2-fluoro-4-[5-(tert-butyldiphenylsilanyloxy)-pentylselanyl]-phenyloxyacetic acid

Guidance literature:: With lithium hydroxide; In tetrahydrofuran; methanol; at 20 ℃; for 3h;
DOI:10.1021/ol048053z

Reference yield:

: 831223-27-9
2-fluoro-4-[5-(tert-butyldiphenylsilanyloxy)-pentylselanyl]-phenol

: 831223-29-1
2-fluoro-4-[5-(tert-butyldiphenylsilanyloxy)-pentylselanyl]-phenyloxyacetic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 97 percent / K₂CO₃ / acetonitrile / 3 h

2: 100 percent / aq. LiOH / tetrahydrofuran; methanol / 3 h / 20 °C

With lithium hydroxide; potassium carbonate; In tetrahydrofuran; methanol; acetonitrile;
DOI:10.1021/ol048053z

Reference yield:

: 2105-94-4
4-bromo-2-fluorophenol

: 831223-29-1
2-fluoro-4-[5-(tert-butyldiphenylsilanyloxy)-pentylselanyl]-phenyloxyacetic acid

Guidance literature:: Multi-step reaction with 3 steps

1.1: tert-BuLi / tetrahydrofuran / 0.33 h / -78 °C

1.2: Se / tetrahydrofuran / 1 h / 20 °C

1.3: 97 percent / tetrahydrofuran / 0 - 20 °C

2.1: 97 percent / K₂CO₃ / acetonitrile / 3 h

3.1: 100 percent / aq. LiOH / tetrahydrofuran; methanol / 3 h / 20 °C

With lithium hydroxide; tert.-butyl lithium; potassium carbonate; In tetrahydrofuran; methanol; acetonitrile;
DOI:10.1021/ol048053z