5-(4-nitrophenoxy)-1-phenyl-1H-tetrazole

Base Information

• Chemical Name: 5-(4-nitrophenoxy)-1-phenyl-1H-tetrazole
• CAS No.: 81141-94-8
• Molecular Formula: C₁₃H₉N₅O₃
• Molecular Weight: 283.246
• Mol file: 81141-94-8.mol

Synonyms:5-(4-nitrophenoxy)-1-phenyl-1H-tetrazole

Chemical Property of 5-(4-nitrophenoxy)-1-phenyl-1H-tetrazole

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5-(4-nitrophenoxy)-1-phenyl-1H-tetrazole

There total 3 articles about 5-(4-nitrophenoxy)-1-phenyl-1H-tetrazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

4-nitro-phenol (100-02-7,78813-13-5,89830-32-0) + 5-Chloro-1-phenyltetrazole (14210-25-4) → 5-(4-nitrophenoxy)-1-phenyl-1H-tetrazole (81141-94-8)

Guidance literature:

With potassium tert-butylate; In N,N-dimethyl-formamide; r.t., 3 h then 65 deg C, 24 h;

Reference yield: 68.0%

4-nitro-phenol (100-02-7,78813-13-5,89830-32-0) + 5-methanesulfonyl-1-phenyl-1H-tetrazole (3206-44-8) → 5-(4-nitrophenoxy)-1-phenyl-1H-tetrazole (81141-94-8)

Guidance literature:

With sodium hydroxide; In ethanol; at 20 ℃; for 3h;

DOI:10.1007/bf01169961

Reference yield:

5-methylsulfanyl-1-phenyl-1H-tetrazole (1455-92-1) → 5-(4-nitrophenoxy)-1-phenyl-1H-tetrazole (81141-94-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 97 percent / tetrabutylammonium bromide, potassium permanganate / CH₂Cl₂; H₂O; acetic acid / 12 h / 20 °C

2: 81 percent

With potassium permanganate; tetrabutylammomium bromide; In dichloromethane; water; acetic acid;

upstream raw materials:

4-nitro-phenol

5-Chloro-1-phenyltetrazole

5-methanesulfonyl-1-phenyl-1H-tetrazole

5-methylsulfanyl-1-phenyl-1H-tetrazole

Refernces

• 1、 Gol'tsberg, M. A.,Koldobskii, G. I.. "Simple Method of Preparation 5-Alkyl(aryl)oxy-1-Phenyltetrazoles". . p. 1552 - 1553. Retrieved 2007/10/03.