4'-[(2-n-propyl-4-methyl-6-(1-methylbenzimidazol-2yl)-benzimidazol-1-yl)-methyl]-biphenyl-2-carboxylic acid potassium salt

Base Information

• Chemical Name: 4'-[(2-n-propyl-4-methyl-6-(1-methylbenzimidazol-2yl)-benzimidazol-1-yl)-methyl]-biphenyl-2-carboxylic acid potassium salt
• CAS No.: 862286-64-4
• Molecular Formula: C₃₃H₂₉N₄O₂*K
• Molecular Weight: 552.717
• Mol file: 862286-64-4.mol

Synonyms:4'-[(2-n-propyl-4-methyl-6-(1-methylbenzimidazol-2yl)-benzimidazol-1-yl)-methyl]-biphenyl-2-carboxylic acid potassium salt

Chemical Property of 4'-[(2-n-propyl-4-methyl-6-(1-methylbenzimidazol-2yl)-benzimidazol-1-yl)-methyl]-biphenyl-2-carboxylic acid potassium salt

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4'-[(2-n-propyl-4-methyl-6-(1-methylbenzimidazol-2yl)-benzimidazol-1-yl)-methyl]-biphenyl-2-carboxylic acid potassium salt

There total 2 articles about 4'-[(2-n-propyl-4-methyl-6-(1-methylbenzimidazol-2yl)-benzimidazol-1-yl)-methyl]-biphenyl-2-carboxylic acid potassium salt which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

telmisatran (144701-48-4) → 4'-[(2-n-propyl-4-methyl-6-(1-methylbenzimidazol-2yl)-benzimidazol-1-yl)-methyl]-biphenyl-2-carboxylic acid potassium salt (862286-64-4)

Guidance literature:

With potassium tert-butylate; In dichloromethane; at 20 ℃; for 1h;

Reference yield:

4'-(1,4'-dimethyl-2'-propyl-1H-[2,5']dibenzimidazolyl-3'-ylmethyl)biphenyl-2-carboxylic acid methyl ester hydrochloride (884330-05-6) → 4'-[(2-n-propyl-4-methyl-6-(1-methylbenzimidazol-2yl)-benzimidazol-1-yl)-methyl]-biphenyl-2-carboxylic acid potassium salt (862286-64-4)

Guidance literature:

With potassium hydroxide; water; In acetonitrile; at 70 - 75 ℃; for 3 - 5h; Product distribution / selectivity;

Reference yield:

4'-[(2-n-propyl-4-methyl-6-(1-methylbenzimidazol-2yl)-benzimidazol-1-yl)-methyl]-biphenyl-2-carboxylic acid potassium salt (862286-64-4) → telmisatran (144701-48-4)

Guidance literature:

4'-[(2-n-propyl-4-methyl-6-(1-methylbenzimidazol-2yl)-benzimidazol-1-yl)-methyl]-biphenyl-2-carboxylic acid potassium salt; With acetic acid; In water; acetonitrile; at 40 - 45 ℃; for 3 - 5h; pH=5 - 5.5;

In methanol; at 75 - 85 ℃; for 0.5 - 0.75h;

upstream raw materials:

4'-(1,4'-dimethyl-2'-propyl-1H-[2,5']dibenzimidazolyl-3'-ylmethyl)biphenyl-2-carboxylic acid methyl ester hydrochloride

telmisatran

Downstream raw materials:

telmisatran