Benzyl 2-Acetamido-3-O-<(R)-1-carbamoylethyl>-2-deoxy-α-D-glucopyranosiduronic Acid Benzyl ester

Base Information

Chemical Name:Benzyl 2-Acetamido-3-O-<(R)-1-carbamoylethyl>-2-deoxy-α-D-glucopyranosiduronic Acid Benzyl ester
CAS No.:129392-05-8
Molecular Formula:C₂₅H₃₀N₂O₈
Molecular Weight:486.522
Hs Code.:

Synonyms:Benzyl 2-Acetamido-3-O-<(R)-1-carbamoylethyl>-2-deoxy-α-D-glucopyranosiduronic Acid Benzyl ester

Suppliers and Price of Benzyl 2-Acetamido-3-O-<(R)-1-carbamoylethyl>-2-deoxy-α-D-glucopyranosiduronic Acid Benzyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of Benzyl 2-Acetamido-3-O-<(R)-1-carbamoylethyl>-2-deoxy-α-D-glucopyranosiduronic Acid Benzyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of Benzyl 2-Acetamido-3-O-<(R)-1-carbamoylethyl>-2-deoxy-α-D-glucopyranosiduronic Acid Benzyl ester

There total 9 articles about Benzyl 2-Acetamido-3-O-<(R)-1-carbamoylethyl>-2-deoxy-α-D-glucopyranosiduronic Acid Benzyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 100-39-0
benzyl bromide

: 129392-04-7
Benzyl 2-Acetamido-3-O-<(R)-1-carbamoylethyl>-2-deoxy-α-D-glucopyranosiduronic Acid

: 129392-05-8
Benzyl 2-Acetamido-3-O-<(R)-1-carbamoylethyl>-2-deoxy-α-D-glucopyranosiduronic Acid Benzyl ester

Guidance literature:: With sodium hydrogencarbonate; In N,N-dimethyl-formamide; at 60 ℃; for 18h;
DOI:10.1021/jo00311a026

Reference yield:

: 10036-64-3
N-acetyl-D-glucosamine

: 129392-05-8
Benzyl 2-Acetamido-3-O-<(R)-1-carbamoylethyl>-2-deoxy-α-D-glucopyranosiduronic Acid Benzyl ester

Guidance literature:: Multi-step reaction with 8 steps

1: HCl gas / 0.33 h / 95 °C

2: p-toluenesulfonic acid monohydrate / acetone / 2 h / Ambient temperature

3: 1) NaH / 1) THF, 2) 50 deg C, 18 h

4: acetic acid / ethanol; H₂O / 2 h / Heating

5: p-toluenesulfonic acid monohydrate / acetonitrile / 3 h / Heating

6: 68 percent / NaIO₄, RuCl₃*H₂O / acetonitrile; CCl₄; H₂O / 0.67 h / Ambient temperature

7: 93 percent / NH₃ / methanol / 18 h / Ambient temperature

8: 80 percent / NaHCO₃ / dimethylformamide / 18 h / 60 °C

With hydrogenchloride; ruthenium trichloride; sodium periodate; ammonia; sodium hydride; sodium hydrogencarbonate; toluene-4-sulfonic acid; acetic acid; In methanol; tetrachloromethane; ethanol; water; N,N-dimethyl-formamide; acetone; acetonitrile;
DOI:10.1021/jo00311a026

Reference yield:

: 66026-10-6
N-((4aR,6S,7R,8R,8aS)-6-(benzyloxy)-8-hydroxy-2,2-dimethylhexahydropyrano[3,2-d][1,3]dioxin-7-yl)acetamide

: 129392-05-8
Benzyl 2-Acetamido-3-O-<(R)-1-carbamoylethyl>-2-deoxy-α-D-glucopyranosiduronic Acid Benzyl ester

Guidance literature:: Multi-step reaction with 6 steps

1: 1) NaH / 1) THF, 2) 50 deg C, 18 h

2: acetic acid / ethanol; H₂O / 2 h / Heating

3: p-toluenesulfonic acid monohydrate / acetonitrile / 3 h / Heating

4: 68 percent / NaIO₄, RuCl₃*H₂O / acetonitrile; CCl₄; H₂O / 0.67 h / Ambient temperature

5: 93 percent / NH₃ / methanol / 18 h / Ambient temperature

6: 80 percent / NaHCO₃ / dimethylformamide / 18 h / 60 °C

With ruthenium trichloride; sodium periodate; ammonia; sodium hydride; sodium hydrogencarbonate; toluene-4-sulfonic acid; acetic acid; In methanol; tetrachloromethane; ethanol; water; N,N-dimethyl-formamide; acetonitrile;
DOI:10.1021/jo00311a026