cis-8-methyl-2-(2-phenylethyl)-4-(phenylthio)-3,6,7,8-tetrahydro-2H-oxocin

Base Information

Chemical Name:cis-8-methyl-2-(2-phenylethyl)-4-(phenylthio)-3,6,7,8-tetrahydro-2H-oxocin
CAS No.:127333-77-1
Molecular Formula:C₂₂H₂₆OS
Molecular Weight:338.514
Hs Code.:

Synonyms:cis-8-methyl-2-(2-phenylethyl)-4-(phenylthio)-3,6,7,8-tetrahydro-2H-oxocin

Suppliers and Price of cis-8-methyl-2-(2-phenylethyl)-4-(phenylthio)-3,6,7,8-tetrahydro-2H-oxocin

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of cis-8-methyl-2-(2-phenylethyl)-4-(phenylthio)-3,6,7,8-tetrahydro-2H-oxocin

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of cis-8-methyl-2-(2-phenylethyl)-4-(phenylthio)-3,6,7,8-tetrahydro-2H-oxocin

There total 6 articles about cis-8-methyl-2-(2-phenylethyl)-4-(phenylthio)-3,6,7,8-tetrahydro-2H-oxocin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

: 127333-75-9,127333-84-0
2-(1-methoxy-3-phenylpropoxy)-6-(phenylthio)-6-heptene

: 127333-77-1
cis-8-methyl-2-(2-phenylethyl)-4-(phenylthio)-3,6,7,8-tetrahydro-2H-oxocin

Guidance literature:: With boron trifluoride diethyl etherate; In various solvent(s); 1.) -78 deg C, 1 h, 2.) -30 deg C, 3 h;
DOI:10.1021/ja00167a041

Reference yield:

: 123186-24-3
1-chloro-1-methoxy-3-phenylpropane

: 127333-77-1
cis-8-methyl-2-(2-phenylethyl)-4-(phenylthio)-3,6,7,8-tetrahydro-2H-oxocin

Guidance literature:: Multi-step reaction with 2 steps

1: 95 percent / i-Pr₂NEt / CH₂Cl₂ / 1.) 0 deg C, 1 h, 2.) 23 deg C, 1 h

2: 79 percent / BF₃*Et₂O / various solvent(s) / 1.) -78 deg C, 1 h, 2.) -30 deg C, 3 h

With boron trifluoride diethyl etherate; N-ethyl-N,N-diisopropylamine; In dichloromethane;
DOI:10.1021/ja00167a041

Reference yield:

: 80485-53-6
phenyl α-bromovinyl sulfide

: 127333-77-1
cis-8-methyl-2-(2-phenylethyl)-4-(phenylthio)-3,6,7,8-tetrahydro-2H-oxocin

Guidance literature:: Multi-step reaction with 4 steps

1: 1.) 9-BBN, 2.) Pd(PPh₃)4, 3 N NaOH / 1a.) THF, 0 deg C, 1 h, b.) 23 deg C, 3 h, 2.) benzene, reflux, 4 h

2: n-Bu₄NF / tetrahydrofuran / 1 h / 60 °C

3: 95 percent / i-Pr₂NEt / CH₂Cl₂ / 1.) 0 deg C, 1 h, 2.) 23 deg C, 1 h

4: 79 percent / BF₃*Et₂O / various solvent(s) / 1.) -78 deg C, 1 h, 2.) -30 deg C, 3 h

With sodium hydroxide; 9-borabicyclo[3.3.1]nonane dimer; tetrakis(triphenylphosphine) palladium⁽⁰⁾; boron trifluoride diethyl etherate; tetrabutyl ammonium fluoride; N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; dichloromethane;
DOI:10.1021/ja00167a041