2-Iodo-1-methoxy-4-(trifluoromethyl)benzene

Base Information

Chemical Name:2-Iodo-1-methoxy-4-(trifluoromethyl)benzene
CAS No.:195624-84-1
Molecular Formula:C₈H₆F₃IO
Molecular Weight:302.035
Hs Code.:
European Community (EC) Number:864-685-5

Synonyms:195624-84-1;2-Iodo-4-(trifluoromethyl)anisole;2-iodo-1-methoxy-4-(trifluoromethyl)benzene;3-Iodo-4-methoxybenzotrifluoride;2-IODO-4-(TRIFLUORMETHYL)ANISOLE;2-Iodo-4-(trifluoromethyl)anisole, 97%;SCHEMBL531737;MFCD06637307;DB-182278;CS-0193293;EN300-8158485

Suppliers and Price of 2-Iodo-1-methoxy-4-(trifluoromethyl)benzene

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
3-Iodo-4-methoxybenzotrifluoride 95+%
5g
$ 554.00

AOBChem
2-Iodo-4-(trifluoromethyl)anisole 95%
10g
$ 916.00

AOBChem
2-Iodo-4-(trifluoromethyl)anisole 95%
100g
$ 4978.00

Alichem
2-Iodo-4-(trifluoromethyl)anisole
1g
$ 1564.50

Alichem
2-Iodo-4-(trifluoromethyl)anisole
250mg
$ 480.00

Alfa Aesar
2-Iodo-4-(trifluoromethyl)anisole, 97%
1g
$ 187.00

Alfa Aesar
2-Iodo-4-(trifluoromethyl)anisole, 97%
250mg
$ 67.30

Total 6 raw suppliers

Chemical Property of 2-Iodo-1-methoxy-4-(trifluoromethyl)benzene

Chemical Property:

Refractive Index:1.5345
XLogP3:3.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:301.94155
Heavy Atom Count:13
Complexity:171

Purity/Quality:

99% ^*data from raw suppliers

3-Iodo-4-methoxybenzotrifluoride 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC1=C(C=C(C=C1)C(F)(F)F)I
Uses 2-Iodo-1-methoxy-4-(trifluoromethyl)benzene is a reagent in the preparation of chiral hydropyrimidines.

Technology Process of 2-Iodo-1-methoxy-4-(trifluoromethyl)benzene

There total 2 articles about 2-Iodo-1-methoxy-4-(trifluoromethyl)benzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 47.0%

: 402-52-8
methyl 4-(trifluoromethyl)phenyl ether

: 195624-84-1
2-iodo-1-methoxy-4-(trifluoromethyl)benzene

Guidance literature:: methyl 4-(trifluoromethyl)phenyl ether; With n-butyllithium; In tetrahydrofuran; hexane; at -78 - 0 ℃; for 0.75h;

With iodine; In tetrahydrofuran; hexane; at -78 - 20 ℃; Inert atmosphere;
DOI:10.1021/jo400926n

Reference yield: 40.0%

: 4864-01-1
2-methoxy-5-(trifluoromethyl)-benzoic acid

: 195624-84-1
2-iodo-1-methoxy-4-(trifluoromethyl)benzene

Guidance literature:: With potassium phosphate; iodine; In acetonitrile; at 120 ℃; for 16h; chemoselective reaction; Glovebox; Inert atmosphere;
DOI:10.1021/jacs.7b05155

Reference yield: 83.0%

: 195624-84-1
2-iodo-1-methoxy-4-(trifluoromethyl)benzene

: 693-02-7
hex-1-yne

: 2-(hex-1-yn-1-yl)-1-methoxy-4-(trifluoromethyl)benzene

Guidance literature:: With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine; In N,N-dimethyl-formamide; at 20 ℃; for 12h; Inert atmosphere;
DOI:10.1002/asia.201701530