2-Methoxy-5-(trifluoromethyl)benzoic acid

Base Information

Chemical Name:2-Methoxy-5-(trifluoromethyl)benzoic acid
CAS No.:4864-01-1
Molecular Formula:C9H7 F3 O3
Molecular Weight:220.148
Hs Code.:2918990090
European Community (EC) Number:629-960-4
DSSTox Substance ID:DTXSID10544405
Wikidata:Q72486289
Mol file:4864-01-1.mol

Synonyms:2-Methoxy-5-(trifluoromethyl)benzoic acid;4864-01-1;Benzoic acid, 2-methoxy-5-(trifluoromethyl)-;MFCD01862091;2-METHOXY-5-TRIFLUOROMETHYLBENZOIC ACID;2-METHOXY-5-(TRIFLUOROMETHYL)BENZOICACID;SCHEMBL345774;DTXSID10544405;CL8891;AKOS005254623;AC-4475;AM61573;DS-18234;SY106976;CS-0042046;2-(methyloxy)-5-(trifluoromethyl)benzoic acid;EN300-186811;A913928;J-509823;W-204286

Suppliers and Price of 2-Methoxy-5-(trifluoromethyl)benzoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-Methoxy-5-(trifluoromethyl)benzoicAcid
500mg
$ 75.00

SynQuest Laboratories
2-Methoxy-5-(trifluoromethyl)benzoic acid 97%
5 g
$ 120.00

SynQuest Laboratories
2-Methoxy-5-(trifluoromethyl)benzoic acid 97%
25 g
$ 447.00

Crysdot
2-Methoxy-5-(trifluoromethyl)benzoicacid 97%
25g
$ 317.00

Apolloscientific
2-Methoxy-5-(trifluoromethyl)benzoicacid 98%
10g
$ 84.00

Apolloscientific
2-Methoxy-5-(trifluoromethyl)benzoicacid 98%
25g
$ 188.00

Apolloscientific
2-Methoxy-5-(trifluoromethyl)benzoicacid 98%
5g
$ 47.00

AOBChem
2-Methoxy-5-(trifluoromethyl)benzoicacid 97%
25g
$ 235.00

American Custom Chemicals Corporation
2-METHOXY-5-(TRIFLUOROMETHYL)BENZOIC ACID 95.00%
1G
$ 162.75

American Custom Chemicals Corporation
2-METHOXY-5-(TRIFLUOROMETHYL)BENZOIC ACID 95.00%
25G
$ 1283.57

Total 27 raw suppliers

Chemical Property of 2-Methoxy-5-(trifluoromethyl)benzoic acid

Chemical Property:

Vapor Pressure:0.001mmHg at 25°C
Melting Point:108-111oC
Boiling Point:285 ºC
Flash Point:126 ºC
PSA：46.53000
Density:1.380
LogP:2.41220
Storage Temp.:Sealed in dry,Room Temperature
Water Solubility.:Insoluble in water.
XLogP3:2.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:2
Exact Mass:220.03472857
Heavy Atom Count:15
Complexity:239

Purity/Quality:

97% ^*data from raw suppliers

2-Methoxy-5-(trifluoromethyl)benzoicAcid ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=C(C=C(C=C1)C(F)(F)F)C(=O)O
Uses 2-Methoxy-5-(trifluoromethyl)benzoic acid is used as an intermediate in synthetic chemistry.

Technology Process of 2-Methoxy-5-(trifluoromethyl)benzoic acid

There total 5 articles about 2-Methoxy-5-(trifluoromethyl)benzoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 124-38-9,18923-20-1
carbon dioxide

: 402-10-8
2-bromo-1-methoxy-4-(trifluoromethyl)benzene

: 1068-55-9
isopropylmagnesium chloride

: 4864-01-1
2-methoxy-5-(trifluoromethyl)-benzoic acid

: 79-31-2
isobutyric Acid

Guidance literature:: 2-bromo-1-methoxy-4-(trifluoromethyl)benzene; isopropylmagnesium chloride; With lithium chloride; In tetrahydrofuran; diethyl ether; at 20 ℃; for 15h;

carbon dioxide; In tetrahydrofuran; diethyl ether; at -78 - 20 ℃;

With hydrogenchloride; potassium carbonate; more than 3 stages;

Reference yield:

: 124-38-9,18923-20-1
carbon dioxide

: 402-52-8
methyl 4-(trifluoromethyl)phenyl ether

: 4864-01-1
2-methoxy-5-(trifluoromethyl)-benzoic acid

Guidance literature:: methyl 4-(trifluoromethyl)phenyl ether; With n-butyllithium; potassium tert-butylate; In tetrahydrofuran; at -78 ℃; for 4h;

carbon dioxide; In tetrahydrofuran; at -78 - 25 ℃; for 1.5h;