N-(2-phenylethyl)-N-tosylpropynimide

Base Information

• Chemical Name: N-(2-phenylethyl)-N-tosylpropynimide
• CAS No.: 1309932-51-1
• Molecular Formula: C₁₈H₁₇NO₃S
• Molecular Weight: 327.404
• Mol file: 1309932-51-1.mol

Synonyms:N-(2-phenylethyl)-N-tosylpropynimide

Chemical Property of N-(2-phenylethyl)-N-tosylpropynimide

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of N-(2-phenylethyl)-N-tosylpropynimide

There total 1 articles about N-(2-phenylethyl)-N-tosylpropynimide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 24.0%

propynoyl pivaloyl anhydride + 4-methyl-N-(2-phenylethyl)benzenesulfonamide (5450-75-9) → N-(2-phenylethyl)-N-tosylpropynimide (1309932-51-1)

Guidance literature:

4-methyl-N-(2-phenylethyl)benzenesulfonamide; With n-butyllithium; In tetrahydrofuran; for 0.5h; Inert atmosphere; Cooling;

propynoyl pivaloyl anhydride; In tetrahydrofuran; at 20 ℃; for 1h; Inert atmosphere; Cooling;

DOI:10.1055/s-0030-1259561

Reference yield: 68.0%

N-(2-phenylethyl)-N-tosylpropynimide (1309932-51-1) → (E)-N-(2-phenylethyl)-3-(N-(2-phenylethyl)-4-methylphenylsulfonamido)-N-tosylpropenamide (1309932-62-4)

Guidance literature:

With triethylamine; In toluene; at 20 ℃; Inert atmosphere;

DOI:10.1055/s-0030-1259561

upstream raw materials:

4-methyl-N-(2-phenylethyl)benzenesulfonamide

Downstream raw materials:

(E)-N-(2-phenylethyl)-3-(N-(2-phenylethyl)-4-methylphenylsulfonamido)-N-tosylpropenamide