C₁₇H₁₉ClN₂O₄S*C₇H₈O₃S

Base Information

• Chemical Name: C₁₇H₁₉ClN₂O₄S*C₇H₈O₃S
• CAS No.: 1609080-24-1
• Molecular Formula: C₇H₈O₃S*C₁₇H₁₉ClN₂O₄S
• Molecular Weight: 555.073
• Mol file: 1609080-24-1.mol

Synonyms:C₁₇H₁₉ClN₂O₄S*C₇H₈O₃S

Chemical Property of C₁₇H₁₉ClN₂O₄S*C₇H₈O₃S

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₇H₁₉ClN₂O₄S*C₇H₈O₃S

There total 7 articles about C₁₇H₁₉ClN₂O₄S*C₇H₈O₃S which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 63.0%

C23H23ClN2O5S2 (1609070-71-4) + toluene-4-sulfonic acid (104-15-4) → C17H19ClN2O4S*C7H8O3S (1609080-24-1)

Guidance literature:

C₂₃H₂₃ClN₂O₅S₂; With pyridine; phosphorus pentachloride; In dichloromethane; at -5 - 15 ℃; for 1h; Inert atmosphere;

toluene-4-sulfonic acid; In ethyl acetate; at 35 ℃; for 2.5h; Inert atmosphere;

Reference yield:

C24H24N2O8S2 → C17H19ClN2O4S*C7H8O3S (1609080-24-1)

Guidance literature:

Multi-step reaction with 6 steps

1.1: N,N-dimethylammonium chloride / N,N-dimethyl-formamide / 3 h / 60 °C / Inert atmosphere

2.1: zinc; hydrogenchloride / 1,4-dioxane; dichloromethane; water / 1.75 h / Inert atmosphere; Cooling with ice

3.1: hydrogenchloride / 1,4-dioxane / 2 h / Inert atmosphere; Cooling with ice

4.1: peracetic acid / dichloromethane / 3 h / Inert atmosphere; Cooling with ice

5.1: phosphorus trichloride / N,N-dimethyl-formamide / 1.17 h / -40 - -35 °C / Inert atmosphere

6.1: phosphorus pentachloride; pyridine / dichloromethane / 1 h / -5 - 15 °C / Inert atmosphere

6.2: 2.5 h / 35 °C / Inert atmosphere

With pyridine; hydrogenchloride; peracetic acid; phosphorus pentachloride; N,N-dimethylammonium chloride; zinc; phosphorus trichloride; In 1,4-dioxane; dichloromethane; water; N,N-dimethyl-formamide;

Reference yield:

p-methoxybenzyl 7β-(2-thienylacetamido)-3-(acetoxymethyl)-3-cephem-4-carboxylate (52646-45-4) → C17H19ClN2O4S*C7H8O3S (1609080-24-1)

Guidance literature:

Multi-step reaction with 7 steps

1.1: peracetic acid / dichloromethane / -10 - -5 °C / Inert atmosphere

2.1: N,N-dimethylammonium chloride / N,N-dimethyl-formamide / 3 h / 60 °C / Inert atmosphere

3.1: zinc; hydrogenchloride / 1,4-dioxane; dichloromethane; water / 1.75 h / Inert atmosphere; Cooling with ice

4.1: hydrogenchloride / 1,4-dioxane / 2 h / Inert atmosphere; Cooling with ice

5.1: peracetic acid / dichloromethane / 3 h / Inert atmosphere; Cooling with ice

6.1: phosphorus trichloride / N,N-dimethyl-formamide / 1.17 h / -40 - -35 °C / Inert atmosphere

7.1: phosphorus pentachloride; pyridine / dichloromethane / 1 h / -5 - 15 °C / Inert atmosphere

7.2: 2.5 h / 35 °C / Inert atmosphere

With pyridine; hydrogenchloride; peracetic acid; phosphorus pentachloride; N,N-dimethylammonium chloride; zinc; phosphorus trichloride; In 1,4-dioxane; dichloromethane; water; N,N-dimethyl-formamide;

upstream raw materials:

p-methoxybenzyl 7β-(2-thienylacetamido)-3-(acetoxymethyl)-3-cephem-4-carboxylate

C₂₃H₂₂N₂O₅S₂

C₂₃H₂₃ClN₂O₅S₂

C₂₃H₂₃ClN₂O₅S₂