(+)-(3S,6S)-6-[2-(tert-butyldiphenylsilyloxy)ethyl]-3,6-dihydro-2H-pyran-3-yl hydroxycarbamate

Base Information

• Chemical Name: (+)-(3S,6S)-6-[2-(tert-butyldiphenylsilyloxy)ethyl]-3,6-dihydro-2H-pyran-3-yl hydroxycarbamate
• CAS No.: 1082074-12-1
• Molecular Formula: C₂₄H₃₁NO₅Si
• Molecular Weight: 441.599
• Mol file: 1082074-12-1.mol

Synonyms:(+)-(3S,6S)-6-[2-(tert-butyldiphenylsilyloxy)ethyl]-3,6-dihydro-2H-pyran-3-yl hydroxycarbamate

Chemical Property of (+)-(3S,6S)-6-[2-(tert-butyldiphenylsilyloxy)ethyl]-3,6-dihydro-2H-pyran-3-yl hydroxycarbamate

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of (+)-(3S,6S)-6-[2-(tert-butyldiphenylsilyloxy)ethyl]-3,6-dihydro-2H-pyran-3-yl hydroxycarbamate

There total 1 articles about (+)-(3S,6S)-6-[2-(tert-butyldiphenylsilyloxy)ethyl]-3,6-dihydro-2H-pyran-3-yl hydroxycarbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C27H32N2O4Si → (+)-(3S,6S)-6-[2-(tert-butyldiphenylsilyloxy)ethyl]-3,6-dihydro-2H-pyran-3-yl hydroxycarbamate (1082074-12-1)

Guidance literature:

With 1H-imidazole; hydroxylamine hydrochloride; In acetonitrile; at 0 ℃; for 22h;

DOI:10.1021/jo8015709

Reference yield: 72.0%

2-mesitylenesulphonyl chloride (773-64-8) + (+)-(3S,6S)-6-[2-(tert-butyldiphenylsilyloxy)ethyl]-3,6-dihydro-2H-pyran-3-yl hydroxycarbamate (1082074-12-1) → (-)-(3S,6S)-6-[2-(tert-butyldiphenylsilyloxy)ethyl]-3,6-dihydro-2H-pyran-3-yl mesitylsulfonyloxycarbamate (1082074-13-2)

Guidance literature:

With triethylamine; In N,N-dimethyl-formamide; toluene; at 0 ℃; for 1h;

DOI:10.1021/jo8015709

Downstream raw materials:

(-)-(3S,6S)-6-[2-(tert-butyldiphenylsilyloxy)ethyl]-3,6-dihydro-2H-pyran-3-yl mesitylsulfonyloxycarbamate