LP₂₂₅

Base Information

• Chemical Name: LP₂₂₅
• CAS No.: 1445739-60-5
• Molecular Formula: C₇₉H₁₀₁N₃O₆S₂
• Molecular Weight: 1252.82
• Mol file: 1445739-60-5.mol

Synonyms:LP₂₂₅

Chemical Property of LP₂₂₅

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of LP₂₂₅

There total 5 articles about LP₂₂₅ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

C76H100N2O5S2 (1445739-58-1) + cyanoacetic acid (372-09-8) → LP225 (1445739-60-5)

Guidance literature:

With piperidine; In chloroform; at 80 ℃;

DOI:10.1021/cm401144j

Reference yield:

1-hexylheptylamine (22513-16-2) → LP225 (1445739-60-5)

Guidance literature:

Multi-step reaction with 5 steps

1.1: tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; sodium t-butanolate / toluene / 120 °C / Inert atmosphere

2.1: lithium diisopropyl amide / tetrahydrofuran / 2 h / -78 °C

2.2: 1 h / -78 - 20 °C

3.1: N-Bromosuccinimide / tetrahydrofuran / 0.5 h / -78 °C

4.1: tetrakis(triphenylphosphine) palladium⁽⁰⁾; potassium carbonate / tetrahydrofuran / 70 °C / Inert atmosphere

5.1: piperidine / chloroform / 80 °C

With piperidine; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; N-Bromosuccinimide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; potassium carbonate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; sodium t-butanolate; lithium diisopropyl amide; In tetrahydrofuran; chloroform; toluene; 1.1: |Buchwald-Hartwig Coupling / 4.1: |Suzuki Coupling / 5.1: |Knoevenagel Condensation;

DOI:10.1021/cm401144j

Reference yield:

N-(1-hexylheptyl)dithieno[3,2-b:2',3'-d]pyrrole (1158270-38-2) → LP225 (1445739-60-5)

Guidance literature:

Multi-step reaction with 4 steps

1.1: lithium diisopropyl amide / tetrahydrofuran / 2 h / -78 °C

1.2: 1 h / -78 - 20 °C

2.1: N-Bromosuccinimide / tetrahydrofuran / 0.5 h / -78 °C

3.1: tetrakis(triphenylphosphine) palladium⁽⁰⁾; potassium carbonate / tetrahydrofuran / 70 °C / Inert atmosphere

4.1: piperidine / chloroform / 80 °C

With piperidine; N-Bromosuccinimide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; potassium carbonate; lithium diisopropyl amide; In tetrahydrofuran; chloroform; 3.1: |Suzuki Coupling / 4.1: |Knoevenagel Condensation;

DOI:10.1021/cm401144j

upstream raw materials:

1-hexylheptylamine

3,3'dibromo-2,2'-bithiophene

C₇₆H₁₀₀N₂O₅S₂

cyanoacetic acid