2-(1-(1-(3-(2-chloro-5-methoxyphenoxy)-4-methylpentyl)piperidin-4-yl)-2-oxoindolin-3-yl)-N,N-dimethylacetamide

Base Information

Chemical Name:2-(1-(1-(3-(2-chloro-5-methoxyphenoxy)-4-methylpentyl)piperidin-4-yl)-2-oxoindolin-3-yl)-N,N-dimethylacetamide
CAS No.:1616854-30-8
Molecular Formula:C₃₀H₄₀ClN₃O₄
Molecular Weight:542.118
Hs Code.:

Synonyms:2-(1-(1-(3-(2-chloro-5-methoxyphenoxy)-4-methylpentyl)piperidin-4-yl)-2-oxoindolin-3-yl)-N,N-dimethylacetamide

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Chemical Property of 2-(1-(1-(3-(2-chloro-5-methoxyphenoxy)-4-methylpentyl)piperidin-4-yl)-2-oxoindolin-3-yl)-N,N-dimethylacetamide

Chemical Property:

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Technology Process of 2-(1-(1-(3-(2-chloro-5-methoxyphenoxy)-4-methylpentyl)piperidin-4-yl)-2-oxoindolin-3-yl)-N,N-dimethylacetamide

There total 14 articles about 2-(1-(1-(3-(2-chloro-5-methoxyphenoxy)-4-methylpentyl)piperidin-4-yl)-2-oxoindolin-3-yl)-N,N-dimethylacetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 478613-43-3
3-(2-chloro-5-methoxyphenoxy)-4-methylpentyl methanesulfonate

: N,N-dimethyl-2-(2-oxo-1-(piperidin-4-yl)indolin-3-yl)acetamide trifluoroacetic acid salt

: 1616854-30-8
2-(1-(1-(3-(2-chloro-5-methoxyphenoxy)-4-methylpentyl)piperidin-4-yl)-2-oxoindolin-3-yl)-N,N-dimethylacetamide

Guidance literature:: With N-ethyl-N,N-diisopropylamine; In acetonitrile; at 80 ℃;

Reference yield:

: 150-19-6
O-methylresorcine

: 1616854-30-8
2-(1-(1-(3-(2-chloro-5-methoxyphenoxy)-4-methylpentyl)piperidin-4-yl)-2-oxoindolin-3-yl)-N,N-dimethylacetamide

Guidance literature:: Multi-step reaction with 4 steps

1: thionyl chloride / diethyl ether / 2 h / 0 - 20 °C

2: caesium carbonate / dimethyl sulfoxide / 100 °C

3: triethylamine / dichloromethane / 0.17 h / 0 - 20 °C

4: N-ethyl-N,N-diisopropylamine / acetonitrile / 80 °C

With thionyl chloride; caesium carbonate; triethylamine; N-ethyl-N,N-diisopropylamine; In diethyl ether; dichloromethane; dimethyl sulfoxide; acetonitrile;

Reference yield:

: 18113-04-7
2-chloro-5-methoxy-phenol

: 1616854-30-8
2-(1-(1-(3-(2-chloro-5-methoxyphenoxy)-4-methylpentyl)piperidin-4-yl)-2-oxoindolin-3-yl)-N,N-dimethylacetamide

Guidance literature:: Multi-step reaction with 3 steps

1: caesium carbonate / dimethyl sulfoxide / 100 °C

2: triethylamine / dichloromethane / 0.17 h / 0 - 20 °C

3: N-ethyl-N,N-diisopropylamine / acetonitrile / 80 °C

With caesium carbonate; triethylamine; N-ethyl-N,N-diisopropylamine; In dichloromethane; dimethyl sulfoxide; acetonitrile;