(+)-(S)-3-(1-(4-chlorophenyl)-2-nitroethyl)pentane-2,4-dione

Base Information

• Chemical Name: (+)-(S)-3-(1-(4-chlorophenyl)-2-nitroethyl)pentane-2,4-dione
• CAS No.: 1039741-62-2
• Molecular Formula: C₁₃H₁₄ClNO₄
• Molecular Weight: 283.711
• Mol file: 1039741-62-2.mol

Synonyms:(+)-(S)-3-(1-(4-chlorophenyl)-2-nitroethyl)pentane-2,4-dione

Chemical Property of (+)-(S)-3-(1-(4-chlorophenyl)-2-nitroethyl)pentane-2,4-dione

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

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Technology Process of (+)-(S)-3-(1-(4-chlorophenyl)-2-nitroethyl)pentane-2,4-dione

There total 6 articles about (+)-(S)-3-(1-(4-chlorophenyl)-2-nitroethyl)pentane-2,4-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

1-chloro-4-(2-nitrovinyl)benzene (706-07-0,5153-70-8) + acetylacetone (123-54-6,81235-32-7) → (+)-(S)-3-(1-(4-chlorophenyl)-2-nitroethyl)pentane-2,4-dione (1039741-62-2)

Guidance literature:

With 3-((3,5-bis(trifluoromethyl)benzyl)amino)-4-(((1S)-(6-methoxyquinolin-4-yl)((2S,4S,5R)-5-vinylquinuclidin-2-yl)methyl)amino)cyclobut-3-ene-1,2-dione; sodium chloride; In water; at 20 ℃; for 0.333333h; optical yield given as %ee; enantioselective reaction;

DOI:10.1039/c1cc13637b

Reference yield: 92.0%

1-chloro-4-(2-nitrovinyl)benzene (706-07-0,5153-70-8) + acetylacetone (123-54-6,81235-32-7) → (R)-3-[1-(4-chloro-phenyl)-2-nitro-ethyl]-pentane-2,4-dione + (+)-(S)-3-(1-(4-chlorophenyl)-2-nitroethyl)pentane-2,4-dione (1039741-62-2)

Guidance literature:

1-chloro-4-(2-nitrovinyl)benzene; With C₃₄H₃₄FeN₄O₃; In dichloromethane; for 0.0833333h; Inert atmosphere;

acetylacetone; In dichloromethane; at 20 ℃; for 6h; Inert atmosphere;

DOI:10.1055/s-0034-1379491

Reference yield: 89.0%

1-nitro-2-(4-chlorophenyl)ethylene (101671-01-6,5153-70-8) + acetylacetone (123-54-6,81235-32-7) → (+)-(S)-3-(1-(4-chlorophenyl)-2-nitroethyl)pentane-2,4-dione (1039741-62-2)

Guidance literature:

With C₃₁H₅₃N₃O₂S; In toluene; at -40 ℃; for 12h; optical yield given as %ee; enantioselective reaction;

DOI:10.1016/j.tetasy.2012.03.020

upstream raw materials:

1-nitro-2-(4-chlorophenyl)ethylene

acetylacetone

1-chloro-4-(2-nitrovinyl)benzene

4-chlorobenzaldehyde