C₁₆H₂₄NO₃Cl

Base Information

• Chemical Name: C₁₆H₂₄NO₃Cl
• CAS No.: 943763-20-0
• Molecular Formula: C₁₆H₂₄ClNO₃
• Molecular Weight: 313.824
• Mol file: 943763-20-0.mol

Synonyms:C₁₆H₂₄NO₃Cl

Chemical Property of C₁₆H₂₄NO₃Cl

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

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Technology Process of C₁₆H₂₄NO₃Cl

There total 1 articles about C₁₆H₂₄NO₃Cl which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

ethyl 2-((2-chlorophenyl)(hydroxy)methyl)acrylate (88039-46-7) + N-butylamine (109-73-9,85404-21-3) → C16H24NO3Cl (943763-20-0)

Guidance literature:

In methanol; ethanol; at 20 ℃;

DOI:10.1055/s-2007-965931

Reference yield: 70.0%

C16H24NO3Cl (943763-20-0) + bromocyane (506-68-3) → ethyl 2-{[butyl(cyano)amino]methyl}-3-(2-chlorophenyl)-3-hydroxypropionate (943763-27-7)

Guidance literature:

With sodium hydrogencarbonate; In benzene; at 20 ℃; for 0.25h;

DOI:10.1055/s-2007-965931

Reference yield:

C16H24NO3Cl (943763-20-0) → 1-butyl-5-(2-chlorobenzyl)pyrimidine-2,4(1H,3H)-dione

Guidance literature:

Multi-step reaction with 2 steps

1: 70 percent / sodium bicarbonate / benzene / 0.25 h / 20 °C

2: 75 percent / sodium hydride / toluene; various solvent(s) / 0.75 h / 20 °C

With sodium hydride; sodium hydrogencarbonate; In toluene; benzene;

DOI:10.1055/s-2007-965931

upstream raw materials:

ethyl 2-((2-chlorophenyl)(hydroxy)methyl)acrylate

N-butylamine

Downstream raw materials:

ethyl 2-{[butyl(cyano)amino]methyl}-3-(2-chlorophenyl)-3-hydroxypropionate