2-FURAN-2-YL-BENZOIC ACID METHYL ESTER

Base Information

• Chemical Name: 2-FURAN-2-YL-BENZOIC ACID METHYL ESTER
• CAS No.: 39732-01-9
• Molecular Formula: C12H10 O3
• Molecular Weight: 202.21
• Hs Code.: 2932190090
• Mol file: 39732-01-9.mol

Synonyms:Methyl2-furylbenzoate; Methyl o-2-furylbenzoate

Chemical Property of 2-FURAN-2-YL-BENZOIC ACID METHYL ESTER

Chemical Property:

• Vapor Pressure: 0.00039mmHg at 25°C
• Refractive Index: 1.538
• Boiling Point: 317.2°Cat760mmHg
• Flash Point: 145.6°C
• PSA: 39.44000
• Density: 1.152g/cm³
• LogP: 2.73320

Purity/Quality:

97% ^*data from raw suppliers

Methyl2-(2-Furyl)benzoate ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-FURAN-2-YL-BENZOIC ACID METHYL ESTER

There total 10 articles about 2-FURAN-2-YL-BENZOIC ACID METHYL ESTER which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

methyl 2-((methylsulfonyl)oxy)benzoate (95667-98-4) + 2-Furan-2-yl-4,5-dimethyl-[1,3,2]dioxaborolane → 2-(2-furyl)benzoic acid methyl ester (39732-01-9)

Guidance literature:

2-Furan-2-yl-4,5-dimethyl-[1,3,2]dioxaborolane; With bis(triphenylphosphine)nickel(II) chloride; methyllithium; In tetrahydrofuran; at 20 ℃; for 0.25h;

methyl 2-((methylsulfonyl)oxy)benzoate; In tetrahydrofuran; at 20 ℃; for 12h;

DOI:10.1016/S0022-328X(02)01174-9

Reference yield: 90.0%

furan (110-00-9) + 2-(methoxycarbonyl)benzenediazonium tetrafluoroborate (342-54-1) → 2-(2-furyl)benzoic acid methyl ester (39732-01-9)

Guidance literature:

With potassium acetate; In acetonitrile; at 0 - 20 ℃; for 24h;

DOI:10.1080/00304948.2018.1405334

Reference yield: 81.0%

2-bromobenzoic acid methyl ester (610-94-6) + 2-(tributylstannyl)furan (118486-94-5) → 2-(2-furyl)benzoic acid methyl ester (39732-01-9)

Guidance literature:

With lithium chloride; dichlorobis(tris[4-(heptadecafluorooctyl)phenyl]phosphine-kP)palladium; In N,N-dimethyl-formamide; at 80 ℃; for 3h;

upstream raw materials:

methanol

2-(2-furanyl)-benzaldehyde

methyl 2-((methylsulfonyl)oxy)benzoate

2-bromobenzoic acid methyl ester

Downstream raw materials:

2-(furan-2-yl)benzoic acid

o-(5-formyl-2-furyl)benzonitrile

2-(furan-2-yl)benzoyl chloride

2-(furan-2-yl)benzonitrile