Technology Process of (3S,4S)-3-benzylthia-4-hydroxycyclopentanone
There total 3 articles about (3S,4S)-3-benzylthia-4-hydroxycyclopentanone which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
vinyl acetate; (+/-)-trans-3-benzylthio-4-hydroxycyclopentanone;
With
Candida antarctica lipase B;
In
di-isopropyl ether;
at 30 ℃;
for 16h;
With
triethylamine;
for 1h;
DOI:10.1016/j.tetasy.2004.07.042
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: 40 percent / potassium dihydrogen orthophosphate / H2O / 48 h / 99 °C
2.1: 86 percent / triethylamine / CH2Cl2 / 16 h / 20 °C
3.1: Candida antarctica lipase B / diisopropyl ether / 16 h / 30 °C
3.2: 49 percent / triethylamine / 1 h
With
Candida antarctica lipase B; potassium dihydrogenphosphate; triethylamine;
In
dichloromethane; di-isopropyl ether; water;
DOI:10.1016/j.tetasy.2004.07.042
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: 86 percent / triethylamine / CH2Cl2 / 16 h / 20 °C
2.1: Candida antarctica lipase B / diisopropyl ether / 16 h / 30 °C
2.2: 49 percent / triethylamine / 1 h
With
Candida antarctica lipase B; triethylamine;
In
dichloromethane; di-isopropyl ether;
DOI:10.1016/j.tetasy.2004.07.042
