C₂₇H₂₈FN₃O₅S

Base Information

Chemical Name:C₂₇H₂₈FN₃O₅S
CAS No.:1256489-00-5
Molecular Formula:C₂₇H₂₈FN₃O₅S
Molecular Weight:525.601
Hs Code.:

C<sub>27</sub>H<sub>28</sub>FN<sub>3</sub>O<sub>5</sub>S

Synonyms:C₂₇H₂₈FN₃O₅S

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Chemical Property of C₂₇H₂₈FN₃O₅S

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Technology Process of C₂₇H₂₈FN₃O₅S

There total 4 articles about C₂₇H₂₈FN₃O₅S which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 57.0%

: 957120-32-0
(5-fluoro-2-methoxypyridin-3-yl)boronic acid

: 1206776-45-5
C₂₁H₂₃BrN₂O₄S

: 1256489-00-5
C₂₇H₂₈FN₃O₅S

Guidance literature:: With sodium carbonate; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In methanol; dichloromethane; at 90 ℃; for 0.5h; Sealed tube; Microwave Irradiation;

Reference yield:

: 1206776-41-1
4-bromo-2-tert-butyl-6-iodophenol

: 1256489-00-5
C₂₇H₂₈FN₃O₅S

Guidance literature:: Multi-step reaction with 3 steps

1: copper(l) iodide; triethylamine / bis-triphenylphosphine-palladium(II) chloride / N,N-dimethyl-formamide / 2 h / 70 °C

2: hydrido(dimethylphosphinous acid-κP)[hydrogen bis(dimethylphosphinito-κP)]platinum(II) / ethanol / 2 h / Reflux

3: sodium carbonate / tetrakis(triphenylphosphine) palladium⁽⁰⁾ / methanol; dichloromethane / 0.5 h / 90 °C / Sealed tube; Microwave Irradiation

With copper(l) iodide; sodium carbonate; triethylamine; bis-triphenylphosphine-palladium(II) chloride; tetrakis(triphenylphosphine) palladium⁽⁰⁾; hydrido(dimethylphosphinous acid-κP)[hydrogen bis(dimethylphosphinito-κP)]platinum(II); In methanol; ethanol; dichloromethane; N,N-dimethyl-formamide;

Reference yield:

: 1206776-44-4
C₂₁H₂₁BrN₂O₃S

: 1256489-00-5
C₂₇H₂₈FN₃O₅S

Guidance literature:: Multi-step reaction with 2 steps

1: hydrido(dimethylphosphinous acid-κP)[hydrogen bis(dimethylphosphinito-κP)]platinum(II) / ethanol / 2 h / Reflux

2: sodium carbonate / tetrakis(triphenylphosphine) palladium⁽⁰⁾ / methanol; dichloromethane / 0.5 h / 90 °C / Sealed tube; Microwave Irradiation

With sodium carbonate; tetrakis(triphenylphosphine) palladium⁽⁰⁾; hydrido(dimethylphosphinous acid-κP)[hydrogen bis(dimethylphosphinito-κP)]platinum(II); In methanol; ethanol; dichloromethane;