2-CHLORO-N-(TETRAHYDROFURAN-2-YLMETHYL)ACETAMIDE

Base Information

• Chemical Name: 2-CHLORO-N-(TETRAHYDROFURAN-2-YLMETHYL)ACETAMIDE
• CAS No.: 39089-62-8
• Molecular Formula: C7H12 Cl N O2
• Molecular Weight: 177.631
• Hs Code.: 2932190090
• Mol file: 39089-62-8.mol

Synonyms:Acetamide,2-chloro-N-(tetrahydrofurfuryl)- (6CI,7CI);2-Chloro-N-(2,3,4,5-tetrahydro-2-furylmethyl)acetamide;2-Chloro-N-[(tetrahydrofuran-2-yl)methyl]acetamide

Chemical Property of 2-CHLORO-N-(TETRAHYDROFURAN-2-YLMETHYL)ACETAMIDE

Chemical Property:

• Vapor Pressure: 5.21E-05mmHg at 25°C
• Melting Point: 42-45°C
• Boiling Point: 347.9 °C at 760 mmHg
• Flash Point: 164.2 °C
• PSA: 38.33000
• Density: 1.175 g/cm³
• LogP: 0.91130

Purity/Quality:

97% ^*data from raw suppliers

2-chloro-N-(tetrahydro-2-furanylmethyl)acetamide ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-CHLORO-N-(TETRAHYDROFURAN-2-YLMETHYL)ACETAMIDE

There total 1 articles about 2-CHLORO-N-(TETRAHYDROFURAN-2-YLMETHYL)ACETAMIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

TETRAHYDROFURFURYLAMINE (4795-29-3) + chloroacetyl chloride (79-04-9) → 2-chloro-N-[(tetrahydrofuran-2-yl)methyl]acetamide (39089-62-8)

Guidance literature:

In dichloromethane;

DOI:10.1016/j.tetlet.2003.09.216

Reference yield: 74.0%

2-chloro-N-[(tetrahydrofuran-2-yl)methyl]acetamide (39089-62-8) + 3-(4-methoxyphenyl)-1,2,4-thiadiazole-5-thiol → C16H19N3O3S2

Guidance literature:

With N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; at 20 ℃; for 90h;

Reference yield: 20.0%

2-chloro-N-[(tetrahydrofuran-2-yl)methyl]acetamide (39089-62-8) + 3-(3-methylphenyl)-1,2,4-thiadiazole-5-thiol (20069-38-9) → C16H19N3O2S2

Guidance literature:

With N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; at 20 ℃; for 90h;

upstream raw materials:

TETRAHYDROFURFURYLAMINE

chloroacetyl chloride

Downstream raw materials:

2-(2,5-dichlorophenylthio)-N-((tetrahydrofuran-2-yl)methyl)acetamide

2-(2,4-dichlorophenylthio)-N-((tetrahydrofuran-2-yl)methyl)acetamide

2-(2,3-dichlorophenylthio)-N-((tetrahydrofuran-2-yl)methyl)acetamide

2-(2,6-dichlorophenylthio)-N-((tetrahydrofuran-2-yl)methyl)acetamide