C₁₉H₂₇NO₄

Base Information

Chemical Name:C₁₉H₂₇NO₄
CAS No.:1448685-38-8
Molecular Formula:C₁₉H₂₇NO₄
Molecular Weight:333.428
Hs Code.:

C<sub>19</sub>H<sub>27</sub>NO<sub>4</sub>

Synonyms:C₁₉H₂₇NO₄

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of C₁₉H₂₇NO₄

Chemical Property:

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Technology Process of C₁₉H₂₇NO₄

There total 1 articles about C₁₉H₂₇NO₄ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 49.2%

: 51828-89-8
ethyl 3‐(4‐formylphenyl)acrylate

: 58620-93-2
tert-butyl 3-aminopropanoate hydrochloride

: 1448685-38-8
C₁₉H₂₇NO₄

Guidance literature:: tert-butyl 3-aminopropanoate hydrochloride; With potassium carbonate; In 1,2-dichloro-ethane; for 0.333333h;

ethyl 3‐(4‐formylphenyl)acrylate; With sodium tris(acetoxy)borohydride; In 1,2-dichloro-ethane; at 20 ℃;

Reference yield:

: 1448685-38-8
C₁₉H₂₇NO₄

: 1448685-39-9
C₁₅H₁₉NO₄

Guidance literature:: With trifluoroacetic acid; In dichloromethane; at 20 ℃;

Reference yield:

: 1448685-38-8
C₁₉H₂₇NO₄

: 1448685-47-9
C₂₉H₃₇Cl₂N₅O₄

Guidance literature:: Multi-step reaction with 9 steps

1.1: trifluoroacetic acid / dichloromethane / 20 °C

2.1: 1,4-dioxane / 5 h / Reflux

3.1: triethylamine; HATU / dichloromethane / 12 h / 0 - 20 °C

4.1: acetic acid / toluene / 0.5 h / 100 °C

5.1: acetic acid; zinc / dichloromethane / 1 h / 20 °C

6.1: acetic acid / water / 5 h / 23 °C

7.1: triethylamine; methanesulfonyl chloride / dichloromethane / 1 h / 0 - 20 °C

7.2: 2 h / 100 °C

8.1: lithium hydroxide monohydrate / water; tetrahydrofuran / 5 h / 23 °C

9.1: triethylamine; HATU; hydroxylamine hydrochloride / dichloromethane / 5 h / 20 °C

With lithium hydroxide monohydrate; hydroxylamine hydrochloride; acetic acid; methanesulfonyl chloride; triethylamine; HATU; trifluoroacetic acid; zinc; In tetrahydrofuran; 1,4-dioxane; dichloromethane; water; toluene;