1,3-bis(2,6-diisopropylphenyl)-2-methylene-2,3-dihydro-1H-imidazole

Base Information

• Chemical Name: 1,3-bis(2,6-diisopropylphenyl)-2-methylene-2,3-dihydro-1H-imidazole
• CAS No.: 1315461-59-6
• Molecular Formula: C₂₈H₃₈N₂
• Molecular Weight: 402.623
• Mol file: 1315461-59-6.mol

Synonyms:1,3-bis(2,6-diisopropylphenyl)-2-methylene-2,3-dihydro-1H-imidazole

Chemical Property of 1,3-bis(2,6-diisopropylphenyl)-2-methylene-2,3-dihydro-1H-imidazole

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1,3-bis(2,6-diisopropylphenyl)-2-methylene-2,3-dihydro-1H-imidazole

There total 10 articles about 1,3-bis(2,6-diisopropylphenyl)-2-methylene-2,3-dihydro-1H-imidazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

1,3-bis-(2,6-diisopropylphenyl)-imidazol-2-ylidene (244187-81-3) + methyl iodide (74-88-4) → N,N'-bis(2,6-diisopropylphenyl)imidazolium iodide (524742-02-7) + 1,3-bis(2,6-diisopropylphenyl)-2-methylene-2,3-dihydro-1H-imidazole (1315461-59-6)

Guidance literature:

In toluene; at 20 ℃; for 1h; Inert atmosphere;

DOI:10.1039/c1cc11737h

Reference yield: 86.3%

1,3-bis-(2,6-diisopropylphenyl)-imidazol-2-ylidene (244187-81-3) + methyl iodide (74-88-4) → 1,3-bis(2,6-diisopropylphenyl)-2-methylene-2,3-dihydro-1H-imidazole (1315461-59-6)

Guidance literature:

In tetrahydrofuran; hexane; at 20 ℃; for 4h; Inert atmosphere; Schlenk technique;

DOI:10.1021/om400539z

Reference yield: 78.0%

1,3-bis[2,6-diisopropylphenyl]imidazolium chloride (250285-32-6) + methyl iodide (74-88-4) → 1,3-bis(2,6-diisopropylphenyl)-2-methylene-2,3-dihydro-1H-imidazole (1315461-59-6)

Guidance literature:

1,3-bis[2,6-diisopropylphenyl]imidazolium chloride; With sodium hexamethyldisilazane; In tetrahydrofuran; at 20 ℃; for 0.25h; Inert atmosphere;

methyl iodide; In tetrahydrofuran; at 20 ℃; for 1h; Inert atmosphere;

DOI:10.1002/anie.201507921

upstream raw materials:

1,3-bis(2,6-diisopropylphenyl)-2-methyl-1H-imidazol-3-ium iodide

1,3-bis-(2,6-diisopropylphenyl)-imidazol-2-ylidene

methyl iodide

dmap

Downstream raw materials:

(1,3-bis-(2,6-diisopropylphenyl)-imidazol-2-methylidene)H₂BNMe₂-BH₃

(1,3-bis-(2,6-diisopropylphenyl)-imidazol-2-methylidene)H₂BNH₂-BH₃

IPrCH₂GeCl₂

C₂₈H₃₈Cl₂N₂Si