3,4-Bis(chloromethyl)pyridine

Base Information

Chemical Name:3,4-Bis(chloromethyl)pyridine
CAS No.:38070-81-4
Molecular Formula:C₇H₇Cl₂N
Molecular Weight:176.045
Hs Code.:2933399090
DSSTox Substance ID:DTXSID60561228
Wikidata:Q82444925
Mol file:38070-81-4.mol

Synonyms:3,4-bis(chloromethyl)pyridine;38070-81-4;Pyridine,3,4-bis(chloromethyl)-(9CI);3,4-bis-(Chloromethyl)pyridine;SCHEMBL3102369;DTXSID60561228;HKXIQVHSQFKAQN-UHFFFAOYSA-N;AKOS006305088;AB60081

Suppliers and Price of 3,4-Bis(chloromethyl)pyridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 9 raw suppliers

Chemical Property of 3,4-Bis(chloromethyl)pyridine

Chemical Property:

PSA：12.89000
LogP:2.55920
XLogP3:1.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:2
Exact Mass:174.9955546
Heavy Atom Count:10
Complexity:97.6

Purity/Quality:: 98%Min ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CN=CC(=C1CCl)CCl

Technology Process of 3,4-Bis(chloromethyl)pyridine

There total 6 articles about 3,4-Bis(chloromethyl)pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 48.0%

: 38070-80-3
[3-(hydroxymethyl)-4-pyridyl]methanol

: 38070-81-4
3,4-bis(chloromethyl)pyridine

Guidance literature:: With thionyl chloride; In dichloromethane; at 45 ℃;

Reference yield:

: 490-11-9
3,4-pyridinecarboxylic acid

: 38070-81-4
3,4-bis(chloromethyl)pyridine

Guidance literature:: Multi-step reaction with 3 steps

1: conc. H₂SO₄ / 20 h / Heating

2: NaBH₄ / ethanol / 17 h / Heating

3: SOCl₂ / CH₂Cl₂ / 1 h / 75 °C

With sodium tetrahydroborate; thionyl chloride; sulfuric acid; In ethanol; dichloromethane;
DOI:10.1016/S0968-0896(02)00426-1

Reference yield:

: 1796-83-4
dimethyl 3,4-pyridinedicarboxylate

: 38070-81-4
3,4-bis(chloromethyl)pyridine

Guidance literature:: Multi-step reaction with 2 steps

1: NaBH₄ / ethanol / 17 h / Heating

2: SOCl₂ / CH₂Cl₂ / 1 h / 75 °C

With sodium tetrahydroborate; thionyl chloride; In ethanol; dichloromethane;
DOI:10.1016/S0968-0896(02)00426-1