trifluoromethanesulfonic acid 2-[6-(4-tert-butyl-benzenesulfonylamino)-5-(2-methoxy-phenoxy)-2-trifluoromethanesulfonyloxy-pyrimidin-4-yloxy]-ethyl ester

Base Information

Chemical Name:trifluoromethanesulfonic acid 2-[6-(4-tert-butyl-benzenesulfonylamino)-5-(2-methoxy-phenoxy)-2-trifluoromethanesulfonyloxy-pyrimidin-4-yloxy]-ethyl ester
CAS No.:1334686-07-5
Molecular Formula:C₂₅H₂₅F₆N₃O₁₁S₃
Molecular Weight:753.675
Hs Code.:

trifluoromethanesulfonic acid 2-[6-(4-tert-butyl-benzenesulfonylamino)-5-(2-methoxy-phenoxy)-2-trifluoromethanesulfonyloxy-pyrimidin-4-yloxy]-ethyl ester

Synonyms:trifluoromethanesulfonic acid 2-[6-(4-tert-butyl-benzenesulfonylamino)-5-(2-methoxy-phenoxy)-2-trifluoromethanesulfonyloxy-pyrimidin-4-yloxy]-ethyl ester

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Chemical Property of trifluoromethanesulfonic acid 2-[6-(4-tert-butyl-benzenesulfonylamino)-5-(2-methoxy-phenoxy)-2-trifluoromethanesulfonyloxy-pyrimidin-4-yloxy]-ethyl ester

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Technology Process of trifluoromethanesulfonic acid 2-[6-(4-tert-butyl-benzenesulfonylamino)-5-(2-methoxy-phenoxy)-2-trifluoromethanesulfonyloxy-pyrimidin-4-yloxy]-ethyl ester

There total 3 articles about trifluoromethanesulfonic acid 2-[6-(4-tert-butyl-benzenesulfonylamino)-5-(2-methoxy-phenoxy)-2-trifluoromethanesulfonyloxy-pyrimidin-4-yloxy]-ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 358-23-6
trifluoromethylsulfonic anhydride

: 1334686-06-4
4-tert-Butyl-N-[2-hydroxy-6-(2-hydroxy-ethoxy)-5-(2-methoxy-phenoxy)-pyrimidin-4-yl]-benzenesulfonamide

: 1334686-07-5
trifluoromethanesulfonic acid 2-[6-(4-tert-butyl-benzenesulfonylamino)-5-(2-methoxy-phenoxy)-2-trifluoromethanesulfonyloxy-pyrimidin-4-yloxy]-ethyl ester

Guidance literature:: With pyridine; at -30 ℃; for 1h; Inert atmosphere;

Reference yield:

: 1334686-10-0
C₂₈H₃₇N₃O₈S₂

: 1334686-07-5
trifluoromethanesulfonic acid 2-[6-(4-tert-butyl-benzenesulfonylamino)-5-(2-methoxy-phenoxy)-2-trifluoromethanesulfonyloxy-pyrimidin-4-yloxy]-ethyl ester

Guidance literature:: Multi-step reaction with 3 steps

1.1: sodium hydroxide / 1,4-dioxane / 1 h / 100 °C

1.2: 0 °C / pH 3 - 4

2.1: formic acid / 2 h / 85 °C

2.2: 1 h

3.1: pyridine / 1 h / -30 °C / Inert atmosphere

With pyridine; formic acid; sodium hydroxide; In 1,4-dioxane;

Reference yield:

: 1334686-03-1
N-[6-(2-tert-Butoxyethoxy)-2-hydroxy-5-(2-methoxy-phenoxy)-pyrimidin-4-yl]-4-tert-butylbenzenesulfonamide

: 1334686-07-5
trifluoromethanesulfonic acid 2-[6-(4-tert-butyl-benzenesulfonylamino)-5-(2-methoxy-phenoxy)-2-trifluoromethanesulfonyloxy-pyrimidin-4-yloxy]-ethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1.1: formic acid / 2 h / 85 °C

1.2: 1 h

2.1: pyridine / 1 h / -30 °C / Inert atmosphere

With pyridine; formic acid;