Technology Process of (2S,3R,6S)-6-(1-Ethoxyethoxy)-3-methylthio(thiocarbonyl)-oxy-2-<(E)-styryl>-3,6-dihydro-2H-pyran
There total 5 articles about (2S,3R,6S)-6-(1-Ethoxyethoxy)-3-methylthio(thiocarbonyl)-oxy-2-<(E)-styryl>-3,6-dihydro-2H-pyran which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 1) 1.5M BuLi / 1) THF, 2) THF, -78 deg C, 30 min
2: 19.1 percent / L-(+)-di-isopropyl tartrate, titanium tetraisopropoxide, t-butyl hydroperoxide, activated molecular sieves 3 Angstroem / CH2Cl2; various solvent(s) / 15 h / -25 °C
3: 32 percent / pyridinium toluene-p-sulphonate / CH2Cl2 / 1 h / Ambient temperature
4: 60 percent / NaBH4 / tetrahydrofuran; H2O / 3 h / 0 °C
With
titanium(IV) isopropylate; tert.-butylhydroperoxide; sodium tetrahydroborate; n-butyllithium; L-(+)-diisopropyl tartrate; 3 A molecular sieve; pyridinium p-toluenesulfonate;
In
tetrahydrofuran; dichloromethane; water;
DOI:10.1039/P19900001733
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 32 percent / pyridinium toluene-p-sulphonate / CH2Cl2 / 1 h / Ambient temperature
2: 60 percent / NaBH4 / tetrahydrofuran; H2O / 3 h / 0 °C
With
sodium tetrahydroborate; pyridinium p-toluenesulfonate;
In
tetrahydrofuran; dichloromethane; water;
DOI:10.1039/P19900001733
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 19.1 percent / L-(+)-di-isopropyl tartrate, titanium tetraisopropoxide, t-butyl hydroperoxide, activated molecular sieves 3 Angstroem / CH2Cl2; various solvent(s) / 15 h / -25 °C
2: 32 percent / pyridinium toluene-p-sulphonate / CH2Cl2 / 1 h / Ambient temperature
3: 60 percent / NaBH4 / tetrahydrofuran; H2O / 3 h / 0 °C
With
titanium(IV) isopropylate; tert.-butylhydroperoxide; sodium tetrahydroborate; L-(+)-diisopropyl tartrate; 3 A molecular sieve; pyridinium p-toluenesulfonate;
In
tetrahydrofuran; dichloromethane; water;
DOI:10.1039/P19900001733
