(S)-2-[(S)-2,5-dioxo-1-phenylpyrrolidin-3-yl]-2-phenylpropanal

Base Information

• Chemical Name: (S)-2-[(S)-2,5-dioxo-1-phenylpyrrolidin-3-yl]-2-phenylpropanal
• CAS No.: 1431769-07-1
• Molecular Formula: C₁₉H₁₇NO₃
• Molecular Weight: 307.349
• Mol file: 1431769-07-1.mol

Synonyms:(S)-2-[(S)-2,5-dioxo-1-phenylpyrrolidin-3-yl]-2-phenylpropanal

Chemical Property of (S)-2-[(S)-2,5-dioxo-1-phenylpyrrolidin-3-yl]-2-phenylpropanal

Chemical Property:

Purity/Quality:

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Technology Process of (S)-2-[(S)-2,5-dioxo-1-phenylpyrrolidin-3-yl]-2-phenylpropanal

There total 1 articles about (S)-2-[(S)-2,5-dioxo-1-phenylpyrrolidin-3-yl]-2-phenylpropanal which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N-phenyl-maleimide (941-69-5) + 2-Phenylpropanal (34713-70-7) → (R)-2-((S)-2,5-dioxo-1-phenylpyrrolidin-3-yl)-2-phenylpropanal (1380095-44-2) + (S)-2-[(R)-2,5-dioxo-1-phenylpyrrolidin-3-yl]-2-phenylpropanal (1431769-31-1) + (R)-2-[(R)-2,5-dioxo-1-phenylpyrrolidin-3-yl]-2-phenylpropanal (1431769-25-3) + (S)-2-[(S)-2,5-dioxo-1-phenylpyrrolidin-3-yl]-2-phenylpropanal (1431769-07-1)

Guidance literature:

With L-Asp(t-Bu); potassium hydroxide; In dichloromethane; at 20 ℃; for 24h; Overall yield = 81 %; enantioselective reaction;

DOI:10.1021/ol4008662

upstream raw materials:

N-phenyl-maleimide

2-Phenylpropanal