Methyl 2-pyrazineacetate

Base Information

Chemical Name:Methyl 2-pyrazineacetate
CAS No.:370562-35-9
Molecular Formula:C₇H₈N₂O₂
Molecular Weight:152.153
Hs Code.:2933990090
DSSTox Substance ID:DTXSID80363807
Wikidata:Q82147547
Mol file:370562-35-9.mol

Synonyms:Methyl 2-pyrazineacetate;370562-35-9;METHYL 2-(PYRAZIN-2-YL)ACETATE;Methyl 2-pyrazin-2-ylacetate;METHYL (PYRAZIN-2-YL)ACETATE;MFCD04038671;methyl pyrazin-2-ylacetate;methyl 2-pyrazin-2-ylethanoate;SCHEMBL5306141;DTXSID80363807;AKOS006295405;CS-W000723;PB20098;SB10183;2-(2-pyrazinyl)acetic acid methyl ester;DS-13489;FT-0644520;A823512

Suppliers and Price of Methyl 2-pyrazineacetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Methyl2-Pyrazineacetate
10mg
$ 45.00

Matrix Scientific
Methyl(pyrazin-2-yl)acetate 95+%
1g
$ 62.00

Matrix Scientific
Methyl(pyrazin-2-yl)acetate 95+%
5g
$ 195.00

Crysdot
Methyl2-pyrazineacetate 98%
10g
$ 317.00

Crysdot
Methyl2-pyrazineacetate 98%
25g
$ 594.00

Chemenu
Methyl(pyrazin-2-yl)acetate 95%+
1g
$ 68.00

American Custom Chemicals Corporation
METHYL 2-PYRAZINEACETATE 95.00%
5G
$ 1029.63

Ambeed
Methyl2-pyrazineacetate 98%
10g
$ 442.00

Ambeed
Methyl2-pyrazineacetate 98%
25g
$ 878.00

Ambeed
Methyl2-pyrazineacetate 98%
1g
$ 57.00

Total 25 raw suppliers

Chemical Property of Methyl 2-pyrazineacetate

Chemical Property:

Vapor Pressure:0.0814mmHg at 25°C
Refractive Index:1.508
Boiling Point:226.5°Cat760mmHg
PKA:0.48±0.10(Predicted)
Flash Point:90.8°C
PSA：52.08000
Density:1.182g/cm³
LogP:0.19210
Storage Temp.:under inert gas (nitrogen or Argon) at 2-8°C
XLogP3:-0.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:152.058577502
Heavy Atom Count:11
Complexity:138

Purity/Quality:

99%, ^*data from raw suppliers

Methyl2-Pyrazineacetate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC(=O)CC1=NC=CN=C1

Technology Process of Methyl 2-pyrazineacetate

There total 2 articles about Methyl 2-pyrazineacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 37.0%

: 109-08-0
2-Methylpyrazine

: 616-38-6
carbonic acid dimethyl ester

: 370562-35-9
methyl 2-(pyrazin-2-yl)acetate

Guidance literature:: 2-Methylpyrazine; With lithium diisopropyl amide; In tetrahydrofuran; hexane; at 0 ℃; for 0.5h; Inert atmosphere;

carbonic acid dimethyl ester; In tetrahydrofuran; hexane; at 0 ℃; for 1h; Inert atmosphere;
DOI:10.1021/acs.orglett.1c03078

Reference yield:

: 109-08-0
2-Methylpyrazine

: 79-22-1
methyl chloroformate

: 370562-35-9
methyl 2-(pyrazin-2-yl)acetate

Guidance literature:: 2-Methylpyrazine; With n-butyllithium; diisopropylamine; In tetrahydrofuran; hexane; at -78 - 0 ℃; for 0.166667h; Inert atmosphere; Schlenk technique;

With N,N,N,N,-tetramethylethylenediamine; In tetrahydrofuran; hexane; at 78 ℃; for 1h; Inert atmosphere; Schlenk technique;

methyl chloroformate; In tetrahydrofuran; hexane; at 20 ℃; Inert atmosphere; Schlenk technique;
DOI:10.1002/anie.201504757

Reference yield: 85.0%

: 370562-35-9
methyl 2-(pyrazin-2-yl)acetate

: 74-88-4
methyl iodide

: 1341956-76-0
methyl 2-(pyrazin-2-yl)propanoate

Guidance literature:: methyl 2-(pyrazin-2-yl)acetate; With n-butyllithium; diisopropylamine; In tetrahydrofuran; hexane; at -78 ℃; for 0.5h; Inert atmosphere;

methyl iodide; In tetrahydrofuran; hexane; at -78 - 20 ℃; for 3.25h; Inert atmosphere;
DOI:10.1021/jacs.9b04440