3-tert-butoxycarbonylamino-N-[2-(4-methoxy-phenyl)-ethyl]-succinamic acid benzyl ester

Base Information

Chemical Name:3-tert-butoxycarbonylamino-N-[2-(4-methoxy-phenyl)-ethyl]-succinamic acid benzyl ester
CAS No.:126631-94-5
Molecular Formula:C₂₅H₃₂N₂O₆
Molecular Weight:456.539
Hs Code.:

3-<i>tert</i>-butoxycarbonylamino-<i>N</i>-[2-(4-methoxy-phenyl)-ethyl]-succinamic acid benzyl ester

Synonyms:3-tert-butoxycarbonylamino-N-[2-(4-methoxy-phenyl)-ethyl]-succinamic acid benzyl ester

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Chemical Property of 3-tert-butoxycarbonylamino-N-[2-(4-methoxy-phenyl)-ethyl]-succinamic acid benzyl ester

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Technology Process of 3-tert-butoxycarbonylamino-N-[2-(4-methoxy-phenyl)-ethyl]-succinamic acid benzyl ester

There total 1 articles about 3-tert-butoxycarbonylamino-N-[2-(4-methoxy-phenyl)-ethyl]-succinamic acid benzyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 13798-75-9
N^α-t-butoxycarbonylaspartic acid α-N-hydroxysuccinimide ester β-benzyl ester

: 55-81-2
4-Methoxyphenethylamine

: 126631-94-5
3-tert-butoxycarbonylamino-N-[2-(4-methoxy-phenyl)-ethyl]-succinamic acid benzyl ester

Guidance literature:: In 1,2-dimethoxyethane; at 20 ℃;
DOI:10.1021/jm000937a

Reference yield:

: 126631-94-5
3-tert-butoxycarbonylamino-N-[2-(4-methoxy-phenyl)-ethyl]-succinamic acid benzyl ester

: BOC-Trp-L-3-(2-naphthyl)alanyl-Asp-2-(4-methoxyphenyl)ethylamide

Guidance literature:: Multi-step reaction with 3 steps

1: TFA / 1 h

2: Et₃N / 1,2-dimethoxy-ethane / 20 °C

3: H₂ / 10percent Pd/C / methanol / 4 h

With hydrogen; triethylamine; trifluoroacetic acid; 10percent Pd/C; In methanol; 1,2-dimethoxyethane; 1: acidolysis / 2: amidation / 3: Hydrogenolysis;
DOI:10.1021/jm000937a

Reference yield:

: 126631-94-5
3-tert-butoxycarbonylamino-N-[2-(4-methoxy-phenyl)-ethyl]-succinamic acid benzyl ester

: 3-{2-[2-tert-butoxycarbonylamino-3-(1H-indol-3-yl)-propionylamino]-3-naphthalen-2-yl-propionylamino}-N-[2-(4-methoxy-phenyl)-ethyl]-succinamic acid benzyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: TFA / 1 h

2: Et₃N / 1,2-dimethoxy-ethane / 20 °C

With triethylamine; trifluoroacetic acid; In 1,2-dimethoxyethane; 1: acidolysis / 2: amidation;
DOI:10.1021/jm000937a