(1'S,2'S,3R)-N-(2'-hydroxy-1'-methyl-2'-phenylethyl)-N,4,4-trimethyl-3-phenylpentanamide

Base Information

• Chemical Name: (1'S,2'S,3R)-N-(2'-hydroxy-1'-methyl-2'-phenylethyl)-N,4,4-trimethyl-3-phenylpentanamide
• CAS No.: 913962-68-2
• Molecular Formula: C₂₃H₃₁NO₂
• Molecular Weight: 353.505

Synonyms:(1'S,2'S,3R)-N-(2'-hydroxy-1'-methyl-2'-phenylethyl)-N,4,4-trimethyl-3-phenylpentanamide

Chemical Property of (1'S,2'S,3R)-N-(2'-hydroxy-1'-methyl-2'-phenylethyl)-N,4,4-trimethyl-3-phenylpentanamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (1'S,2'S,3R)-N-(2'-hydroxy-1'-methyl-2'-phenylethyl)-N,4,4-trimethyl-3-phenylpentanamide

There total 2 articles about (1'S,2'S,3R)-N-(2'-hydroxy-1'-methyl-2'-phenylethyl)-N,4,4-trimethyl-3-phenylpentanamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

tert.-butyl lithium (594-19-4) + E-(+)-(1'S,2'S)-N-methyl-N-(2'-phenyl-2'-hydroxy-1'-methylethyl)-3-phenylprop-2-enamide (678991-36-1) → (1'S,2'S,3S)-N-(2'-hydroxy-1'-methyl-2'-phenylethyl)-N,4,4-trimethyl-3-phenylpentanamide (913962-67-1) + (1'S,2'S,3R)-N-(2'-hydroxy-1'-methyl-2'-phenylethyl)-N,4,4-trimethyl-3-phenylpentanamide (913962-68-2)

Guidance literature:

With lithium chloride; In tetrahydrofuran; hexane; at -105 - 20 ℃;

DOI:10.1021/jo061205e

Reference yield: 84.0%

phenyllithium (591-51-5) + E-(+)-(1'S,2'S)-N-methyl-N-(2'-phenyl-2'-hydroxy-1'-methylethyl)-4,4-dimethylpent-2-enamide (678991-35-0) → (1'S,2'S,3S)-N-(2'-hydroxy-1'-methyl-2'-phenylethyl)-N,4,4-trimethyl-3-phenylpentanamide (913962-67-1) + (1'S,2'S,3R)-N-(2'-hydroxy-1'-methyl-2'-phenylethyl)-N,4,4-trimethyl-3-phenylpentanamide (913962-68-2)

Guidance literature:

With lithium chloride; In tetrahydrofuran; hexane; at -105 - 20 ℃;

DOI:10.1021/jo061205e

Reference yield: 99.0%

(1'S,2'S,3R)-N-(2'-hydroxy-1'-methyl-2'-phenylethyl)-N,4,4-trimethyl-3-phenylpentanamide (913962-68-2) → (R)-4,4-dimethyl-3-phenylpentanoic acid (23406-59-9)

Guidance literature:

With sulfuric acid; In 1,4-dioxane; for 6h; Heating;

DOI:10.1021/jo061205e

upstream raw materials:

tert.-butyl lithium

E-(+)-(1'S,2'S)-N-methyl-N-(2'-phenyl-2'-hydroxy-1'-methylethyl)-3-phenylprop-2-enamide

phenyllithium

E-(+)-(1'S,2'S)-N-methyl-N-(2'-phenyl-2'-hydroxy-1'-methylethyl)-4,4-dimethylpent-2-enamide

Downstream raw materials:

(R)-4,4-dimethyl-3-phenylpentanoic acid

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 913962-68-2 (1'S,2'S,3R)-N-(2'-hydroxy-1'-methyl-2'-phenylethyl)-N,4,4-trimethyl-3-phenylpentanamide

Send

Send

Metric Ton KG G Pound L ML

Send

Send