2-(4-Bromophenyl)ethylamine hydrochloride

Base Information

• Chemical Name: 2-(4-Bromophenyl)ethylamine hydrochloride
• CAS No.: 39260-89-4
• Molecular Formula: C8H10 Br N . Cl H
• Molecular Weight: 236.539
• Hs Code.: 2921499090
• DSSTox Substance ID: DTXSID20599345
• Mol file: 39260-89-4.mol

Synonyms:39260-89-4;2-(4-BROMOPHENYL)ETHYLAMINE HYDROCHLORIDE;4-Bromophenylethylamine HCl;2-(4-bromophenyl)ethanamine;hydrochloride;P-BROMOPHENETHYL AMINE HYDROCHLORIDE;2-(4-BROMO-PHENYL)-ETHYLAMINE HYDROCHLORIDE;2-(4-bromophenyl)ethan-1-amine hydrochloride;4-BROMOPHENYLETHANAMINE, HCL;2-(4-Bromo-phenyl)-ethylamine HCl;99% pound 4 Times Purification pound(c);2-(4-BROMOPHENYL)ETHANAMINE HYDROCHLORIDE;P-BROMOPHENETHYLAMINEHYDROCHLORIDE;p-bromophenethyl amine hcl;DTXSID20599345;ZHAWIPAHUYMLDV-UHFFFAOYSA-N;4-Bromophenylethylammonium Chloride;4-bromo-phenethylamine hydrochloride;4-Bromophenylethanamine hydrochloride;MFCD09037950;AKOS015919505;AS-11035;2-(4-Bromo-phenyl)-ethylamine;2-(4-Bromophenyl)ethan-1-amine--hydrogen chloride (1/1)

Chemical Property of 2-(4-Bromophenyl)ethylamine hydrochloride

Chemical Property:

• Vapor Pressure: 0.00094mmHg at 25°C
• Melting Point: 240-243 °C
• Boiling Point: 224.3°Cat760mmHg
• Flash Point: 91°C
• PSA: 26.02000
• Density: 1.284g/cm³
• LogP: 3.45260
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 234.97634
• Heavy Atom Count: 11
• Complexity: 87.3

Purity/Quality:

97% ^*data from raw suppliers

2-(4-Bromophenyl)ethylamineHydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC(=CC=C1CCN)Br.Cl

Technology Process of 2-(4-Bromophenyl)ethylamine hydrochloride

There total 4 articles about 2-(4-Bromophenyl)ethylamine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

4-Bromophenylacetonitrile (16532-79-9) → 2-(4-bromophenyl)-1-aminoethane hydrochloride (39260-89-4)

Guidance literature:

4-Bromophenylacetonitrile; With titanium(IV) isopropylate; 1,1,3,3-Tetramethyldisiloxane; In toluene; at 60 ℃; for 24h; Inert atmosphere;

With hydrogenchloride; In water; at 20 ℃;

DOI:10.1016/j.tetlet.2009.09.164

Reference yield: 47.0%

C18H22BrN → 2-(4-bromophenyl)-1-aminoethane hydrochloride (39260-89-4)

Guidance literature:

With hydrogenchloride; In propan-1-ol; at 190 ℃; for 0.0833333h; Microwave irradiation; Green chemistry;

DOI:10.1080/00397911.2015.1100745

Reference yield: 23.0%

(E)-1-bromo-4-(2-nitrovinyl)benzene (3156-37-4,5153-71-9) → 2-(4-bromophenyl)-1-aminoethane hydrochloride (39260-89-4)

Guidance literature:

(E)-1-bromo-4-(2-nitrovinyl)benzene; With lithium aluminium tetrahydride; In tetrahydrofuran; at 20 ℃; for 2h;

With hydrogenchloride; In ethyl acetate;

upstream raw materials:

4-Bromophenethylamine

4-Bromophenylacetonitrile

(E)-1-bromo-4-(2-nitrovinyl)benzene

Downstream raw materials:

1-[2-(4-Bromo-phenyl)-ethyl]-imidazolidine-2,4,5-trione

ethyl 1-(2-(4-bromophenyl)ethyl)-2,4,5-trioxoimidazolidine-3-acetate

1-[2-(4-bromophenyl)ethyl]pyrrolidine

benzyl N-[2-(4-bromophenyl)ethyl]carbamate