4-(2-Bromoethyl)pyridine

Base Information

Chemical Name:4-(2-Bromoethyl)pyridine
CAS No.:39232-05-8
Molecular Formula:C7H8 Br N
Molecular Weight:186.051
Hs Code.:2933399090
DSSTox Substance ID:DTXSID40590950
Wikidata:Q82484569
Mol file:39232-05-8.mol

Synonyms:4-(2-bromoethyl)pyridine;39232-05-8;4-(2-BROMOETHYL)-PYRIDINE;4-(2-bromoethyl) pyridine;Pyridine, 4-(2-bromoethyl)-;4-(2-bromo-ethyl)-pyridine;Pyridine,4-(2-bromoethyl)-;SCHEMBL4057377;DTXSID40590950;HEYPEPZGVKJBFH-UHFFFAOYSA-N;AKOS012019343;SB21268;CS-0266400;EN300-123776

Suppliers and Price of 4-(2-Bromoethyl)pyridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Sigma-Aldrich
4-(2-Bromoethyl)pyridine AldrichCPR
1 g
$ 201.00

American Custom Chemicals Corporation
4-(2-BROMOETHYL)PYRIDINE 95.00%
5MG
$ 499.06

Alichem
4-(2-Bromoethyl)pyridine
10g
$ 1218.06

Alichem
4-(2-Bromoethyl)pyridine
5g
$ 884.40

Total 10 raw suppliers

Chemical Property of 4-(2-Bromoethyl)pyridine

Chemical Property:

Boiling Point:235.2±15.0 °C(Predicted)
PKA:5.54±0.10(Predicted)
PSA：12.89000
Density:1.446±0.06 g/cm3(Predicted)
LogP:2.01900
XLogP3:1.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:2
Exact Mass:184.98401
Heavy Atom Count:9
Complexity:69.3

Purity/Quality:

97% ^*data from raw suppliers

4-(2-Bromoethyl)pyridine AldrichCPR ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CN=CC=C1CCBr
Uses 4-(2-Bromoethyl)-pyridine (cas# 39232-05-8) is a useful reagent for preparing disubstituted pyridines as PDE4 inhibitors, which are for asthma and inflammation treatment.

Technology Process of 4-(2-Bromoethyl)pyridine

There total 1 articles about 4-(2-Bromoethyl)pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 5344-27-4
4-(2-hydroxyethyl)pyridine

: 39232-05-8
4-(2-bromoethyl)pyridine

Guidance literature:: With triphenylphosphine dibromide 1:1 addition complex; In dichloromethane; 1) 0 deg C, 15 min, 2) rt, 1 h;
DOI:10.1021/jm00124a015

Reference yield: 90.0%

: 109-97-7,30604-81-0
pyrrole

: 39232-05-8
4-(2-bromoethyl)pyridine

: 6302-13-2
4-<2-(4-pyrrolyl)ethyl>pyridine

Guidance literature:: With potassium carbonate; In N,N-dimethyl-formamide; at 100 ℃; for 6h; Inert atmosphere;
DOI:10.1039/c5cc00242g

Reference yield: 82.0%

: 5-(1-(4-chlorobenzyl)-1H-indole-2-carbonyl)octahydro-1H-pyrrolo[3,4-c]pyridin-1-one

: 39232-05-8
4-(2-bromoethyl)pyridine

: (3aS*,7aR*)-5-(1-(4-chlorobenzyl)-1H-indole-2-carbonyl)-2-(2-(pyridin-4-yl)ethyl)octahydro-1H-pyrrolo[3,4-c]pyridin-1-one

Guidance literature:: 5-(1-(4-chlorobenzyl)-1H-indole-2-carbonyl)octahydro-1H-pyrrolo[3,4-c]pyridin-1-one; With sodium hydride; In N,N-dimethyl-formamide; mineral oil; at 20 ℃; for 1h; Inert atmosphere;

4-(2-bromoethyl)pyridine; In N,N-dimethyl-formamide; mineral oil; at 20 ℃; for 22h; Inert atmosphere;
DOI:10.1016/j.bmcl.2021.128171