(6-METHYL-2-PHENYL-IMIDAZO[1,2-A]PYRIDIN-3-YL)-ACETIC ACID

Base Information

• Chemical Name: (6-METHYL-2-PHENYL-IMIDAZO[1,2-A]PYRIDIN-3-YL)-ACETIC ACID
• CAS No.: 365213-66-7
• Molecular Formula: C16H14 N2 O2
• Molecular Weight: 266.29
• Hs Code.: 2933990090
• Mol file: 365213-66-7.mol

Synonyms:(6-METHYL-2-PHENYL-IMIDAZO[1,2-A]PYRIDIN-3-YL)-ACETIC ACID

Chemical Property of (6-METHYL-2-PHENYL-IMIDAZO[1,2-A]PYRIDIN-3-YL)-ACETIC ACID

Chemical Property:

• PKA: 2.88±0.10(Predicted)
• PSA: 54.60000
• Density: 1.24±0.1 g/cm3(Predicted)
• LogP: 2.93680

Purity/Quality:

99%, ^*data from raw suppliers

(6-Methyl-2-phenyl-imidazo[1,2-a]pyridin-3-yl)-aceticacid 96% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (6-METHYL-2-PHENYL-IMIDAZO[1,2-A]PYRIDIN-3-YL)-ACETIC ACID

There total 8 articles about (6-METHYL-2-PHENYL-IMIDAZO[1,2-A]PYRIDIN-3-YL)-ACETIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

2-(6-methyl-2-phenyl-imidazo[1,2-a]pyridin-3-yl)-acetamide (365213-57-6) → (6-methyl-2-phenylimidazo[1,2-a]pyridin-3-yl)acetic acid (365213-66-7)

Guidance literature:

With potassium hydroxide; In ethanol; for 8h; Heating;

Reference yield:

C20H18N2O4 → (6-methyl-2-phenylimidazo[1,2-a]pyridin-3-yl)acetic acid (365213-66-7)

Guidance literature:

With acetic acid; for 4h; Reflux;

DOI:10.1007/s10593-019-02432-6

Reference yield:

ethyl 2-(6-methyl-2-phenylimidazo[1,2-a]pyridin-3-yl)acetate → (6-methyl-2-phenylimidazo[1,2-a]pyridin-3-yl)acetic acid (365213-66-7)

Guidance literature:

With water; sodium hydroxide; In ethanol; at 90 ℃; Flow reactor;

DOI:10.1039/c2sc21850j

upstream raw materials:

2-(6-methyl-2-phenyl-imidazo[1,2-a]pyridin-3-yl)-acetamide

6-methyl-2-phenylimidazo[1,2-a]pyridine

N,N-dimethyl-1-(6-methyl-2-phenylimidazo[1,2-a]pyridin-3-yl)methanamine

acetophenone

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